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Schizophrenia research
Oct, 2014;159 (1): 151-6.

Wellness within illness: happiness in schizophrenia.

Barton W Palmer, Averria Sirkin Martin, Colin A Depp, Danielle K Glorioso, Dilip V Jeste
Author Information
  1. Barton W Palmer: Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; The University of California, San Diego Center for Healthy Aging and the Stein Institute for Research on Aging, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, San Diego, CA, USA. Electronic address: bpalmer@ucsd.edu.
  2. Averria Sirkin Martin: Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; The University of California, San Diego Center for Healthy Aging and the Stein Institute for Research on Aging, La Jolla, CA, USA.
  3. Colin A Depp: Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; The University of California, San Diego Center for Healthy Aging and the Stein Institute for Research on Aging, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, San Diego, CA, USA.
  4. Danielle K Glorioso: Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; The University of California, San Diego Center for Healthy Aging and the Stein Institute for Research on Aging, La Jolla, CA, USA.
  5. Dilip V Jeste: Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; The University of California, San Diego Center for Healthy Aging and the Stein Institute for Research on Aging, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
PMID: 25153363 DOI: 10.1016/j.schres.2014.07.027

Abstract

Schizophrenia is typically a chronic disorder and among the most severe forms of serious mental illnesses in terms of adverse impact on quality of life. Yet, there have been suggestions that some people with schizophrenia can experience an overall sense of happiness in their lives. We investigated happiness among 72 outpatients with non-remitted chronic schizophrenia with a mean duration of illness of 24.4 years, and 64 healthy comparison subjects (HCs). Despite continued treatment with antipsychotic medications, the individuals with schizophrenia manifested a mild to moderate level of psychopathology. People with schizophrenia reported lower mean levels of happiness than HCs, but there was substantial heterogeneity within the schizophrenia group. Level of happiness in persons with schizophrenia was significantly correlated with higher mental health-related quality of life, and several positive psychosocial factors (lower perceived stress, and higher levels of resilience, optimism, and personal mastery). However, level of happiness was not related to sociodemographic characteristics, duration of illness, severity of positive or negative symptoms, physical function, medical comorbidity, or cognitive functioning. Except for an absence of an association with resilience, the pattern of correlations of happiness with other variables seen among HCs was similar to that in individuals with schizophrenia. Although happiness may be harder to achieve in the context of a serious mental illness, it nonetheless appears to be a viable treatment goal in schizophrenia. Psychotherapies targeting positive coping factors such as resilience, optimism, and personal mastery warrant further investigation.

Keywords

Comorbidity Depression Optimism Positive psychology Recovery Resilience Well-being

References

  1. Schizophr Bull. 2008 Nov;34(6):1024-32 [PMID: 18156637]
  2. Biol Psychiatry. 2000 Jul 15;48(2):137-46 [PMID: 10903410]
  3. BMJ. 2008 Dec 04;337:a2338 [PMID: 19056788]
  4. J Pers Assess. 1985 Feb;49(1):71-5 [PMID: 16367493]
  5. Am J Epidemiol. 1979 Feb;109(2):186-204 [PMID: 425958]
  6. Med Care. 1992 Jun;30(6):473-83 [PMID: 1593914]
  7. Am Psychol. 2000 Jan;55(1):5-14 [PMID: 11392865]
  8. Psychol Med. 1983 Aug;13(3):595-605 [PMID: 6622612]
  9. Psychol Health Med. 2010 May;15(3):266-77 [PMID: 20480432]
  10. Psychol Med. 1998 Jan;28(1):165-72 [PMID: 9483693]
  11. J Pers Soc Psychol. 1994 Dec;67(6):1063-78 [PMID: 7815302]
  12. Neuropsychol Rev. 2009 Sep;19(3):365-84 [PMID: 19639412]
  13. Psychosom Med. 2003 Jul-Aug;65(4):620-6 [PMID: 12883113]
  14. Soc Sci Med. 2013 Sep;92:9-21 [PMID: 23849274]
  15. Psychosom Med. 2001 Mar-Apr;63(2):210-5 [PMID: 11292267]
  16. World J Biol Psychiatry. 2009;10(4 Pt 2):442-51 [PMID: 18609418]
  17. Schizophr Res. 2014 Jan;152(1):1-4 [PMID: 24332407]
  18. Schizophr Res. 2012 Oct;141(1):98-103 [PMID: 22901593]
  19. J Ment Health Policy Econ. 2011 Dec;14(4):201-8 [PMID: 22345362]
  20. J Health Soc Behav. 1983 Dec;24(4):385-96 [PMID: 6668417]
  21. Psychiatry Res. 2007 May 30;151(1-2):37-46 [PMID: 17343920]
  22. J Psychopharmacol. 2006 Nov;20(6 Suppl):3-5 [PMID: 17046983]
  23. J Trauma Stress. 2007 Dec;20(6):1019-28 [PMID: 18157881]
  24. Br J Psychiatry Suppl. 2007 Aug;50:s21-8 [PMID: 18019040]
  25. Int J Psychol. 2013;48(3):159-76 [PMID: 23551025]
  26. J Am Geriatr Soc. 1995 Feb;43(2):130-7 [PMID: 7836636]
  27. J Am Geriatr Soc. 2000 May;48(5):473-8 [PMID: 10811538]
  28. Psychol Aging. 2011 Dec;26(4):956-965 [PMID: 21517182]
  29. Emotion. 2009 Jun;9(3):361-8 [PMID: 19485613]
  30. J Behav Health Serv Res. 2013 Apr;40(2):140-55 [PMID: 23494766]
  31. Clin Breast Cancer. 2011 Dec;11(6):364-8 [PMID: 21831722]
  32. Eur Arch Psychiatry Clin Neurosci. 2000;250(6):292-303 [PMID: 11153964]
  33. J Am Geriatr Soc. 2004 Feb;52(2):257-62 [PMID: 14728637]
  34. Arch Psychiatr Nurs. 2013 Oct;27(5):235-40 [PMID: 24070992]
  35. Schizophr Bull. 1978;4(1):78-85 [PMID: 746364]
  36. Health Educ Behav. 2012 Aug;39(4):474-85 [PMID: 21986242]
  37. Arch Gen Psychiatry. 1982 Jul;39(7):789-94 [PMID: 7165478]
  38. J Pers. 2004 Dec;72(6):1161-90 [PMID: 15509280]
  39. Am J Geriatr Psychiatry. 2001 Fall;9(4):423-8 [PMID: 11739069]
  40. Psychol Med. 2006 Jul;36(7):1033-42 [PMID: 16749947]
  41. N Engl J Med. 2010 Mar 11;362(10):865-9 [PMID: 20220181]
  42. J Altern Complement Med. 2009 May;15(5):593-600 [PMID: 19432513]
  43. Gerontologist. 1990 Oct;30(5):583-94 [PMID: 2276631]
  44. J Gerontol. 1983 Mar;38(2):181-9 [PMID: 6827034]
  45. J Pers Soc Psychol. 2003 Dec;85(6):1136-46 [PMID: 14674819]
  46. Br J Psychiatry. 2013 Feb;202:81-3 [PMID: 23377203]
  47. Psychiatr Serv. 2001 Apr;52(4):534-5 [PMID: 11274504]
  48. Am J Psychiatry. 2013 Feb;170(2):188-96 [PMID: 23223917]

Grants

  1. R01 MH094151/NIMH NIH HHS
  2. T32 MH019934/NIMH NIH HHS
  3. 5T32MH019934/NIMH NIH HHS
  4. 5R01MH094151/NIMH NIH HHS

MeSH Term

Adult
Aged
Antipsychotic Agents
Cognition Disorders
Female
Happiness
Humans
Male
Middle Aged
Mood Disorders
Neuropsychological Tests
Outpatients
Psychiatric Status Rating Scales
Psychotic Disorders
Quality of Life
Schizophrenia
Schizophrenic Psychology
Statistics, Nonparametric
Young Adult

Chemicals

Antipsychotic Agents
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't
Article has an altmetric score of 45

Word Cloud

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