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Langmuir : the ACS journal of surfaces and colloids
2015;31 (1): 499-505.

Single-chain semiconducting polymer dots.

Fangmao Ye, Wei Sun, Yue Zhang, Changfeng Wu, Xuanjun Zhang, Jiangbo Yu, Yu Rong, Miqin Zhang, Daniel T Chiu
Author Information
  1. Fangmao Ye: Department of Chemistry and ‡Department of Material Science and Engineering, University of Washington , Seattle, Washington 98195, United States.
PMID: 25521606 DOI: 10.1021/la5038684

Abstract

This work describes the preparation and validation of single-chain semiconducting polymer dots (sPdots), which were generated using a method based on surface immobilization, washing, and cleavage. The sPdots have an ultrasmall size of ∼3.0 nm as determined by atomic force microscopy, a size that is consistent with the anticipated diameter calculated from the molecular weight of the single-chain semiconducting polymer. sPdots should find use in biology and medicine as a new class of fluorescent probes. The FRET assay this work presents is a simple and rapid test to ensure methods developed for preparing sPdot indeed produced single-chain Pdots as designed.

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Grants

  1. R01 NS052637/NINDS NIH HHS
  2. R21 CA186798/NCI NIH HHS
  3. R01NS052637/NINDS NIH HHS
  4. R21CA186798/NCI NIH HHS

MeSH Term

Fluorescence Resonance Energy Transfer
Microscopy, Atomic Force
Particle Size
Polymers
Semiconductors
Surface Properties

Chemicals

Polymers
Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Word Cloud

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