Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal lymphadenopathy.

Karan Madan, Irfan Ismail Ayub, Anant Mohan, Deepali Jain, Randeep Guleria, Sushil K Kabra
Author Information
  1. Karan Madan: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India, drkaranmadan@gmail.com.

Abstract

Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) is accepted as a safe and minimally invasive modality for evaluation of mediastinal pathologies in adults. There is scanty literature on the utilization and performance characteristics of Convex probe EBUS-TBNA in children. The authors herein describe two pediatric patients with mediastinal lymphadenopathy wherein the underlying diagnosis was unclear based on the clinico-radiological profile. A possibility of lymphoma was considered in one of the patients. EBUS-TBNA was performed for obtaining tissue samples from the enlarged mediastinal lymph nodes and diagnosis of tuberculosis was established in both the patients. The authors review the available literature on Pediatric EBUS TBNA. EBUS-TBNA is an exciting and promising approach towards safe and accurate evaluation of mediastinal pathologies in children. Pediatric EBUS-TBNA needs further evaluation in prospective studies.

References

  1. Pediatr Pulmonol. 2009 Apr;44(4):410-4 [PMID: 19283837]
  2. Arch Bronconeumol. 2011 Aug;47(8):418-9 [PMID: 21524836]
  3. J Bronchology Interv Pulmonol. 2014 Jul;21(3):208-14 [PMID: 24992128]
  4. J Bronchology Interv Pulmonol. 2015 Oct;22(4):347-50 [PMID: 26492608]
  5. J Bronchology Interv Pulmonol. 2011 Apr;18(2):205 [PMID: 23169099]
  6. Chest. 2004 Jul;126(1):122-8 [PMID: 15249452]
  7. Pediatr Pulmonol. 2014 Aug;49(8):807-15 [PMID: 24039186]
  8. Thorax. 2008 Apr;63(4):360-5 [PMID: 17965071]
  9. Thorax. 2011 Oct;66(10 ):889-93 [PMID: 21813622]
  10. Pediatr Pulmonol. 2009 Apr;44(4):303-8 [PMID: 19283761]
  11. Eur J Cardiothorac Surg. 2006 Apr;29(4):627-9; discussion 629 [PMID: 16476541]
  12. Gen Thorac Cardiovasc Surg. 2013 Jul;61(7):390-6 [PMID: 23436118]

MeSH Term

Antibiotics, Antitubercular
Bronchoscopy
Child
Diagnosis, Differential
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Female
Humans
Lymph Nodes
Male
Mediastinal Diseases
Mediastinum
Mycobacterium tuberculosis
Rifampin
Treatment Outcome
Tuberculosis, Lymph Node

Chemicals

Antibiotics, Antitubercular
Rifampin

Word Cloud

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