Fecal microbiota transplant protocol for clostridium difficile infection.

William M Tauxe, Tanvi Dhere, Angela Ward, Lori D Racsa, Jay B Varkey, Colleen S Kraft
Author Information
  1. William M Tauxe: Emory University School of Medicine, Atlanta, Georgia.
  2. Tanvi Dhere: Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia.
  3. Angela Ward: Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia.
  4. Lori D Racsa: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
  5. Jay B Varkey: Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia.
  6. Colleen S Kraft: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia colleen.kraft@emory.edu.

Abstract

Fecal microbiota transplant has become more acceptable as a therapeutic for recurrent Clostridium difficile infection. The FDA has an enforcement discretion policy for practitioner's performing this therapy, which includes informed consent for this experimental treatment. This manuscript describes a typical procedure that can be followed that includes the important aspects of this preparation and treatment.

Keywords

References

  1. Clin Infect Dis. 2003 Mar 1;36(5):580-5 [PMID: 12594638]
  2. J Clin Gastroenterol. 2012 Feb;46(2):145-9 [PMID: 22157239]
  3. N Engl J Med. 2013 Jan 31;368(5):407-15 [PMID: 23323867]
  4. PLoS Pathog. 2012;8(10):e1002995 [PMID: 23133377]

Grants

  1. UL1 TR000454/NCATS NIH HHS

MeSH Term

Clinical Protocols
Clostridioides difficile
Clostridium Infections
Fecal Microbiota Transplantation
Humans

Word Cloud

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