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Journal of orthopaedics
Jun, 2015;12 (2): 86-91.

Thromboembolic disease after knee arthroplasty is rare in Southern Iran.

G Hossain Shahcheraghi, Mahzad Javid, Mohammad M Arasteh
Author Information
  1. G Hossain Shahcheraghi: Department of Orthopaedic Surgery, Namazee and Dena Hospitals, Shiraz, Iran.
  2. Mahzad Javid: Department of Orthopaedic Surgery, Namazee and Dena Hospitals, Shiraz, Iran.
  3. Mohammad M Arasteh: Department of Radiology, Namazee and Dena Hospitals, Shiraz, Iran.
PMID: 25972699 DOI: 10.1016/j.jor.2014.01.003

Abstract

BACKGROUND: Thromboembolic disease (TED) after knee arthroplasty occurs infrequently in Iran. The aim of this study was to examine the incidence of TED in patients with osteoarthritis undergoing knee replacement in Southern Iran while on prophylaxis.
MATERIALS & METHODS: In a case series study from January to December 2012, 100 consecutive total knee arthroplasty (TKA) candidates were evaluated for TED by clinical evaluation and Doppler sonography preoperatively and 2 months postoperatively and by clinical evaluation one year after surgery. The patients in this study randomly received either warfarin or enoxaparin prophylactically.
RESULTS: A total of 77 women and 23 men with mean age of 67 years (52-82 years) entered the study. The average hemoglobin drop of 2.7 g with warfarin and 3.3 with enoxaparin was observed. No case of TED, pulmonary embolus (PE), major bleeding, post-thrombotic syndrome, or hemarthrosis was observed.
CONCLUSION: No clinically significant DVT was found using either enoxaparin or warfarin prophylaxis after TKA in Southern Iran. Relatively excessive postoperative bleeding was observed, particularly with enoxaparin.

Keywords

Enoxaparin Iran Total knee replacement Venous thromboembolism Warfarin

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Journal Article
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Word Cloud

Created with Highcharts 10.0.0kneeIranTEDstudyenoxaparinarthroplastySouthernwarfarinobservedThromboembolicdiseasepatientsreplacementprophylaxiscasetotalTKAclinicalevaluation2eitheryears3bleedingBACKGROUND:occursinfrequentlyaimexamineincidenceosteoarthritisundergoingMATERIALS&METHODS:seriesJanuaryDecember2012100consecutivecandidatesevaluatedDopplersonographypreoperativelymonthspostoperativelyoneyearsurgeryrandomlyreceivedprophylacticallyRESULTS:77women23menmeanage6752-82enteredaveragehemoglobindrop7 gpulmonaryembolusPEmajorpost-thromboticsyndromehemarthrosisCONCLUSION:clinicallysignificantDVTfoundusingRelativelyexcessivepostoperativeparticularlyrareEnoxaparinTotalVenousthromboembolismWarfarin

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