Prevalence of hypothyroidism in infertile women and evaluation of response of treatment for hypothyroidism on infertility.

D Mohana Priya, Nishat Akhtar, Jamal Ahmad
Author Information
  1. D Mohana Priya: Department of Obstetrics and Gynaecology, Faculty of Medicine, J.N. Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
  2. Nishat Akhtar: Department of Obstetrics and Gynaecology, Faculty of Medicine, J.N. Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
  3. Jamal Ahmad: Rajiv Gandhi Centre for Diabetes and Endocrinology, Faculty of Medicine, J.N. Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Abstract

AIMS AND OBJECTIVES: The aim was to study the prevalence of hypothyroidism in infertile women and evaluation of response of treatment for hypothyroidism on infertility.
MATERIALS AND METHODS: A total of 95 infertile women were investigated for thyroid stimulating hormone (TSH). Infertile women with clinical/subclinical hypothyroidism were given thyroxine ranges from 25 to 150 μg.
RESULTS: Of 95 infertile women, 53.7% were hypothyroid (TSH > 4.6 μIU/ml). After the treatment with thyroxine, 33.3% of subclinical hypothyroid women conceived within 6 weeks to 2-year period. The mean time to conception was 14.56 ± 4.83 months.
CONCLUSION: Thyroid profile should be done in infertility work up. Women with normal TSH levels who are positive for thyroid antibodies should also be treated with levothyroxine.

Keywords

References

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Word Cloud

Created with Highcharts 10.0.0womenhypothyroidisminfertileresponsetreatmentinfertilityTSHANDevaluation95thyroidthyroxinehypothyroid46AIMSOBJECTIVES:aimstudyprevalenceMATERIALSMETHODS:totalinvestigatedstimulatinghormoneInfertileclinical/subclinicalgivenranges25150μgRESULTS:537%>μIU/ml333%subclinicalconceivedwithinweeks2-yearperiodmeantimeconception1456±83monthsCONCLUSION:ThyroidprofiledoneworkWomennormallevelspositiveantibodiesalsotreatedlevothyroxinePrevalenceHypothyroidism

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