Blastomyces Antigen Detection for Diagnosis and Management of Blastomycosis.
Holly M Frost, Thomas J Novicki
Author Information
Holly M Frost: Department of Pediatrics, Marshfield Clinic, Minocqua, Wisconsin, USA Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA frost.holly@marshfieldclinic.org.
Thomas J Novicki: Division of Laboratory Medicine, Marshfield Clinic, Marshfield, Wisconsin, USA.
Blastomyces spp. antigen testing was evaluated over a 10-year period in an area where blastomycosis is endemic. Antigen testing was less sensitive than previously reported, but serial urine testing was useful in monitoring disease resolution or progression. Culture and cytopathology remain the gold standard for diagnosis and exclusion of this infection.
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