Draft Genome Sequence of a Metronidazole-Resistant Derivative of Gardnerella vaginalis Strain ATCC 14019.

Jessica A Schuyler, Eli Mordechai, Martin E Adelson, Scott E Gygax, David W Hilbert
Author Information
  1. Jessica A Schuyler: Femeris Women's Health Research Center, Medical Diagnostic Laboratories, a member of Genesis Biotechnology Group, Hamilton, New Jersey, USA.
  2. Eli Mordechai: Femeris Women's Health Research Center, Medical Diagnostic Laboratories, a member of Genesis Biotechnology Group, Hamilton, New Jersey, USA.
  3. Martin E Adelson: Femeris Women's Health Research Center, Medical Diagnostic Laboratories, a member of Genesis Biotechnology Group, Hamilton, New Jersey, USA.
  4. Scott E Gygax: Femeris Women's Health Research Center, Medical Diagnostic Laboratories, a member of Genesis Biotechnology Group, Hamilton, New Jersey, USA.
  5. David W Hilbert: Femeris Women's Health Research Center, Medical Diagnostic Laboratories, a member of Genesis Biotechnology Group, Hamilton, New Jersey, USA dhilbert@mdlab.com.

Abstract

We report the genome sequence of a metronidazole-resistant derivative of Gardnerella vaginalis ATCC 14019. This strain was obtained after serial selection to increase the MIC from 4 to ���500 ��g/ml. Two coding changes, in genes encoding a response regulator and an NAD(+) synthetase, arose during selection.

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Word Cloud

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