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Apr, 2016;41 (4): 631-45.

Regulating Factors in Acid-Sensing Ion Channel 1a Function.

Yinghong Wang, Zaven O'Bryant, Huan Wang, Yan Huang
Author Information
  1. Yinghong Wang: School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China.
  2. Zaven O'Bryant: Department of Neurobiology, Morehouse School of Medicine, 720 Westview Dr., Atlanta, GA, USA.
  3. Huan Wang: School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China.
  4. Yan Huang: School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, China. aydhy@126.com.
PMID: 26582234 DOI: 10.1007/s11064-015-1768-x

Abstract

In recent years, research of acid sensing ion channels (ASICs) has increased tremendously, especially studies focusing on ASIC1a, which plays a critical role in many important physiologic and pathological functions. This review will discuss factors regulating ASIC1a expression and activity in various conditions and will provide a theoretical basis for clinical development and application of ASIC1a modifiers.

Keywords

ASICs Ion channels Neuronal injury Pharmacology Stroke

References

  1. J Biol Chem. 1983 Dec 25;258(24):15173-8 [PMID: 6558077]
  2. J Biol Chem. 2001 Sep 21;276(38):35361-7 [PMID: 11457851]
  3. Pharmacol Ther. 2009 Nov;124(2):195-206 [PMID: 19619582]
  4. Am J Physiol Cell Physiol. 2007 Jun;292(6):C2161-74 [PMID: 17392378]
  5. Am J Physiol Cell Physiol. 2002 Jul;283(1):C126-34 [PMID: 12055080]
  6. J Cereb Blood Flow Metab. 2010 Jun;30(6):1247-60 [PMID: 20216553]
  7. Neurochem Int. 2009 Dec;55(7):683-8 [PMID: 19563851]
  8. Neuroscience. 2007 Mar 16;145(2):631-41 [PMID: 17224241]
  9. EMBO J. 2004 Apr 7;23(7):1516-25 [PMID: 15044953]
  10. Acta Biochim Biophys Sin (Shanghai). 2014 Sep;46(9):774-81 [PMID: 25079679]
  11. Nature. 2012 Oct 25;490(7421):552-5 [PMID: 23034652]
  12. Toxicon. 2013 Dec 1;75:187-204 [PMID: 23624383]
  13. Mol Pharmacol. 2011 Nov;80(5):796-808 [PMID: 21825095]
  14. Biol Psychiatry. 2007 Nov 15;62(10 ):1140-8 [PMID: 17662962]
  15. Trends Neurosci. 2006 Oct;29(10):578-86 [PMID: 16891000]
  16. J Neurosci. 2011 Jun 29;31(26):9723-34 [PMID: 21715637]
  17. Mol Pharmacol. 2000 Oct;58(4):828-36 [PMID: 10999954]
  18. J Membr Biol. 2006 Jan;209(1):59-68 [PMID: 16685601]
  19. J Biol Chem. 2014 May 9;289(19):13363-73 [PMID: 24695733]
  20. J Biol Chem. 2006 Feb 3;281(5):2497-505 [PMID: 16319075]
  21. Neuron. 2000 Apr;26(1):133-41 [PMID: 10798398]
  22. Biochem J. 2002 Feb 1;361(Pt 3):443-50 [PMID: 11802773]
  23. Neurochem Res. 2013 Jul;38(7):1446-53 [PMID: 23640176]
  24. J Biol Chem. 1997 Nov 21;272(47):29778-83 [PMID: 9368048]
  25. Med Hypotheses. 2012 Sep;79(3):352-7 [PMID: 22795752]
  26. Clin Exp Pharmacol Physiol. 2014 Apr;41(4):295-300 [PMID: 24552301]
  27. Toxicol Lett. 2014 Aug 4;228(3):200-6 [PMID: 24821433]
  28. J Neurosci. 2009 Apr 29;29(17):5381-8 [PMID: 19403806]
  29. Nature. 2007 Sep 20;449(7160):316-23 [PMID: 17882215]
  30. J Biol Chem. 2010 Jun 4;285(23):17425-31 [PMID: 20385551]
  31. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C931-40 [PMID: 22205392]
  32. Brain. 2011 Feb;134(Pt 2):571-84 [PMID: 21233144]
  33. Nature. 2011 Nov 16;479(7373):410-4 [PMID: 22094702]
  34. Int J Physiol Pathophysiol Pharmacol. 2012;4(2):84-93 [PMID: 22837807]
  35. Acta Pharmacol Sin. 2013 Jan;34(1):33-8 [PMID: 22820909]
  36. Rev Physiol Biochem Pharmacol. 2004;151:93-107 [PMID: 15146350]
  37. J Biol Chem. 2004 Dec 31;279(53):55514-9 [PMID: 15504740]
  38. Neuropharmacology. 2015 Jul;94:42-8 [PMID: 25582290]
  39. Nature. 1994 Feb 3;367(6462):463-7 [PMID: 8107805]
  40. J Biol Chem. 2010 Apr 23;285(17):13002-11 [PMID: 20185828]
  41. J Biomed Sci. 2012 Aug 21;19:77 [PMID: 22909215]
  42. Nat Neurosci. 2007 Aug;10(8):943-5 [PMID: 17632507]
  43. Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L271-85 [PMID: 19482897]
  44. J Membr Biol. 1988 Oct;105(1):1-21 [PMID: 2852254]
  45. J Biol Chem. 2007 Aug 3;282(31):22668-77 [PMID: 17548344]
  46. Mol Biol Cell. 2007 Aug;18(8):3105-18 [PMID: 17553932]
  47. J Neurosci. 2004 Feb 4;24(5):1013-22 [PMID: 14762119]
  48. J Biol Chem. 2012 Nov 23;287(48):40680-9 [PMID: 23048040]
  49. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8992-7 [PMID: 12060708]
  50. Proc Natl Acad Sci U S A. 1989 Mar;86(5):1736-40 [PMID: 2537985]
  51. PLoS One. 2011;6(7):e21970 [PMID: 21789198]
  52. J Physiol. 2011 Nov 1;589(Pt 21):5109-23 [PMID: 21911609]
  53. Pharmacol Ther. 2012 May;134(2):127-38 [PMID: 22233754]
  54. Am J Physiol Lung Cell Mol Physiol. 2014 Sep 1;307(5):L419-30 [PMID: 24993130]
  55. Am J Physiol Cell Physiol. 2012 Oct 1;303(7):C699-710 [PMID: 22843794]
  56. Nature. 1997 Mar 13;386(6621):173-7 [PMID: 9062189]
  57. J Neurosci. 2006 May 24;26(21):5800-9 [PMID: 16723538]
  58. Biochim Biophys Acta. 2005 Aug 15;1745(1):1-6 [PMID: 16085050]
  59. Cell Calcium. 2010 Jul;48(1):70-82 [PMID: 20678793]
  60. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3573-8 [PMID: 19218436]
  61. J Gen Physiol. 2004 Oct;124(4):383-94 [PMID: 15452199]
  62. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1459-64 [PMID: 9037075]
  63. J Biol Chem. 2011 Jul 15;286(28):24996-5006 [PMID: 21586569]
  64. Channels (Austin). 2008 Nov-Dec;2(6):419-28 [PMID: 18927513]
  65. Neuroscience. 2011 Oct 13;193:89-99 [PMID: 21767613]
  66. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2029-34 [PMID: 12578970]
  67. BMB Rep. 2013 Jun;46(6):295-304 [PMID: 23790972]
  68. Curr Drug Targets Inflamm Allergy. 2004 Mar;3(1):71-9 [PMID: 15032643]
  69. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3621-6 [PMID: 14988500]
  70. Cell. 1999 Apr 16;97(2):175-87 [PMID: 10219239]
  71. J Biol Chem. 2013 Mar 29;288(13):9418-27 [PMID: 23404498]
  72. Genome Biol. 2007;8(2):206 [PMID: 17316461]
  73. J Biol Chem. 2010 Mar 5;285(10):7430-9 [PMID: 20048154]
  74. Brain Res. 2004 Aug 13;1017(1-2):197-207 [PMID: 15261115]
  75. Cell. 2014 Feb 13;156(4):717-29 [PMID: 24507937]
  76. Peptides. 2008 Feb;29(2):186-95 [PMID: 18201803]
  77. Neuron. 2003 Jan 9;37(1):75-84 [PMID: 12526774]
  78. Brain. 2013 Jan;136(Pt 1):106-15 [PMID: 23365093]
  79. Peptides. 2006 May;27(5):1138-52 [PMID: 16516345]
  80. Oncol Rep. 2013 Dec;30(6):2852-8 [PMID: 24100685]
  81. J Neurosci. 2004 Feb 4;24(5):1005-12 [PMID: 14762118]
  82. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L985-92 [PMID: 21890510]
  83. J Neurosci. 2011 Feb 9;31(6):2101-12 [PMID: 21307247]
  84. J Physiol. 2014 Feb 15;592(4):557-69 [PMID: 24247984]
  85. Neuron. 2010 Oct 6;68(1):61-72 [PMID: 20920791]
  86. Nat Med. 2007 Dec;13(12):1483-9 [PMID: 17994101]
  87. Trends Biochem Sci. 1999 Nov;24(11):425-7 [PMID: 10542406]
  88. Neurochem Res. 2015 Oct;40(10):2055-67 [PMID: 24925261]
  89. EMBO J. 2008 Nov 19;27(22):3047-55 [PMID: 18923424]
  90. Cell. 2004 Sep 17;118(6):687-98 [PMID: 15369669]
  91. J Biol Chem. 2008 Jan 25;283(4):1818-30 [PMID: 17984098]
  92. Annu Rev Physiol. 2000;62:573-94 [PMID: 10845103]
  93. J Neurosci Res. 2012 Jan;90(1):267-77 [PMID: 21969311]
  94. Dev Neurobiol. 2007 Jan;67(1):97-107 [PMID: 17443775]
  95. J Biol Chem. 2009 Jan 2;284(1):585-94 [PMID: 18952610]
  96. J Biol Chem. 2002 Feb 15;277(7):5203-8 [PMID: 11739374]
  97. J Biol Chem. 2002 Nov 1;277(44):41597-603 [PMID: 12198124]
  98. Brain Res. 2007 Jan 19;1129(1):110-5 [PMID: 17157279]
  99. Biophys J. 2010 Apr 7;98(7):1182-91 [PMID: 20371317]
  100. Am J Physiol Cell Physiol. 2010 Dec;299(6):C1355-62 [PMID: 20826761]
  101. Nat Rev Drug Discov. 2009 Sep;8(9):733-50 [PMID: 19721446]
  102. Pain. 2005 Sep;117(1-2):88-96 [PMID: 16061325]
  103. Neuron. 2005 Nov 23;48(4):635-46 [PMID: 16301179]
  104. Am J Physiol Cell Physiol. 2013 Jan 1;304(1):C89-101 [PMID: 23135698]
  105. Protein Sci. 2003 Jul;12(7):1332-43 [PMID: 12824480]
  106. Neuropharmacology. 2008 Feb;54(2):454-63 [PMID: 18078964]
  107. J Biol Chem. 1996 Apr 5;271(14):7879-82 [PMID: 8626462]
  108. Mol Pain. 2010 Dec 08;6:88 [PMID: 21143836]
  109. Brain Res. 2001 May 11;900(2):277-81 [PMID: 11334808]
  110. Nature. 2002 Dec 12;420(6916):669-73 [PMID: 12478294]
  111. Nat Commun. 2012 Jul 03;3:936 [PMID: 22760635]
  112. Neuroreport. 2000 Jun 5;11(8):1607-11 [PMID: 10852210]
  113. Trends Neurosci. 2000 Sep;23(9):399-407 [PMID: 10941185]
  114. Pharmacol Ther. 2006 Jul;111(1):224-59 [PMID: 16472864]
  115. J Neurosci. 2006 May 17;26(20):5329-39 [PMID: 16707785]
  116. J Biol Chem. 2013 Nov 29;288(48):34375-83 [PMID: 24142696]
  117. Nature. 2012 Sep 20;489(7416):400-5 [PMID: 22842900]
  118. Pharmacol Res. 2014 Mar;81:83-90 [PMID: 24630950]
  119. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10240-5 [PMID: 9707631]
  120. PLoS One. 2010 Feb 24;5(2):e9395 [PMID: 20195381]
  121. J Pharmacol Exp Ther. 2008 Nov;327(2):491-502 [PMID: 18723775]
  122. J Pharmacol Exp Ther. 2010 Feb;332(2):489-99 [PMID: 19864615]
  123. Mol Brain. 2010 Dec 21;3:39 [PMID: 21176140]
  124. J Neurosci. 2004 Oct 6;24(40):8678-89 [PMID: 15470133]
  125. J Neurosci. 2011 Apr 20;31(16):6059-66 [PMID: 21508231]
  126. Mol Vis. 2011;17:3300-8 [PMID: 22194656]
  127. J Biol Chem. 2014 Sep 5;289(36):25327-40 [PMID: 25023278]
  128. J Biol Chem. 2010 Aug 27;285(35):27130-43 [PMID: 20601429]
  129. J Neurochem. 1999 Jan;72(1):51-7 [PMID: 9886053]
  130. Nat Rev Neurosci. 2013 Jul;14(7):461-71 [PMID: 23783197]
  131. J Biol Chem. 2004 Sep 10;279(37):38448-57 [PMID: 15247234]
  132. J Biol Chem. 2012 Oct 19;287(43):36059-70 [PMID: 22948146]
  133. Neurosci Lett. 2011 Feb 18;490(1):46-51 [PMID: 21167908]
  134. J Biol Chem. 2000 Aug 18;275(33):25116-21 [PMID: 10829030]
  135. CNS Neurosci Ther. 2014 Mar;20(3):264-74 [PMID: 24433527]
  136. Cell Calcium. 2009 Apr;45(4):319-25 [PMID: 19185346]
  137. J Biol Chem. 2006 Jan 13;281(2):714-22 [PMID: 16282326]
  138. J Neurophysiol. 2008 Feb;99(2):426-41 [PMID: 18094106]
  139. J Physiol. 2006 Jan 15;570(Pt 2):339-54 [PMID: 16284080]
  140. J Neurosci. 2009 Nov 11;29(45):14371-80 [PMID: 19906984]
  141. J Neurophysiol. 2003 May;89(5):2459-65 [PMID: 12612000]
  142. Chem Rev. 2008 May;108(5):1744-73 [PMID: 18476673]
  143. J Physiol Sci. 2014 Mar;64(2):129-39 [PMID: 24375028]
  144. Exp Neurol. 2009 Oct;219(2):453-65 [PMID: 19576887]
  145. J Neurosci. 2007 Oct 10;27(41):11139-48 [PMID: 17928456]
  146. Curr Med Chem. 2007;14(16):1753-63 [PMID: 17627513]
  147. J Neurosci Methods. 2005 Jun 15;144(2):241-8 [PMID: 15910984]

MeSH Term

Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels
Animals
Humans
Oxidation-Reduction
Signal Transduction
Sodium Channel Agonists

Chemicals

Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels
Sodium Channel Agonists
Journal Article Research Support, Non-U.S. Gov't Review

Word Cloud

Created with Highcharts 10.0.0ASIC1achannelsASICswillIonrecentyearsresearchacidsensingionincreasedtremendouslyespeciallystudiesfocusingplayscriticalrolemanyimportantphysiologicpathologicalfunctionsreviewdiscussfactorsregulatingexpressionactivityvariousconditionsprovidetheoreticalbasisclinicaldevelopmentapplicationmodifiersRegulatingFactorsAcid-SensingChannel1aFunctionNeuronalinjuryPharmacologyStroke

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