Benign metastasizing leiomyomatosis (BML): A rare cause of cavitary and cystic pulmonary nodules.

Joshua S Jolissaint, Sarah K Kilbourne, Kristen LaFortune, Manojkumar Patel, Christine L Lau
Author Information
  1. Joshua S Jolissaint: University of Virginia School of Medicine, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA, 22903, USA.
  2. Sarah K Kilbourne: University of Virginia, Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA, 22903, USA.
  3. Kristen LaFortune: University of Virginia, Department of Pathology, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA, 22903, USA.
  4. Manojkumar Patel: University of Virginia, Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA, 22903, USA.
  5. Christine L Lau: University of Virginia, Department of Surgery, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA, 22903, USA.

Abstract

Benign metastasizing leiomyomatosis (BML) is a rare cause of pulmonary lesions found in reproductive age women who have undergone a hysterectomy for uterine leiomyoma. Given the relative rarity of the disease, the management of these lesions varies from surgical (oopherectomy) or medical antiestrogen hormonal therapy to clinical observation and survelliance. The disease generally presents asymptomatically with multiple, well-defined pulmonary nodules discovered incidentally on imaging. We report an atypical presentation of a 46-year-old woman with incidentally found bilateral pulmonary cavitating nodules and cysts, concerning for lymphangioleiomyomatosis (LAM), who was ultimately diagnosed with BML.

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