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Molecules (Basel, Switzerland)
Feb 22, 2016;21 (2): 247.

Chemistry and Pharmacology of Citrus sinensis.

Juan Manuel J Favela-Hernández, Omar González-Santiago, Mónica A Ramírez-Cabrera, Patricia C Esquivel-Ferriño, María del Rayo Camacho-Corona
Author Information
  1. Juan Manuel J Favela-Hernández: Facultad de Ciencia Químicas, Universidad Juárez del Estado de Durango, Av. Artículo 123 S/N, Núcleo Universitario, Col. Filadelfia, C.P. 35015, Gómez Palacio, Durango, Mexico. jackman610@ujed.com.mx.
  2. Omar González-Santiago: Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N Ciudad Universitaria, C.P. 66451, San Nicolás de los Garza, Nuevo León, Mexico. omar.gonzalezst@uanl.edu.mx.
  3. Mónica A Ramírez-Cabrera: Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N Ciudad Universitaria, C.P. 66451, San Nicolás de los Garza, Nuevo León, Mexico. monica.ramirezcbr@uanl.edu.mx.
  4. Patricia C Esquivel-Ferriño: Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N Ciudad Universitaria, C.P. 66451, San Nicolás de los Garza, Nuevo León, Mexico. patricia.esquivelfr@uanl.edu.mx.
  5. María del Rayo Camacho-Corona: Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N Ciudad Universitaria, C.P. 66451, San Nicolás de los Garza, Nuevo León, Mexico. maria.camachocn@uanl.edu.mx.
PMID: 26907240 DOI: 10.3390/molecules21020247

Abstract

Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found to have beneficial properties. The present study is a review of the chemistry and pharmacology of Citrus sinensis. This review reveals the therapeutic potential of C. sinensis as a source of natural compounds with important activities that are beneficial for human health that could be used to develop new drugs.

Keywords

Citrus sinensis chemistry natural products orange pharmacological activities

References

  1. Indian J Pharm Sci. 2009 Nov;71(6):677-9 [PMID: 20376223]
  2. Bioresour Technol. 2001 Feb;76(3):273-4 [PMID: 11198181]
  3. J Appl Microbiol. 2006 Dec;101(6):1232-40 [PMID: 17105553]
  4. J Chromatogr A. 2009 Oct 23;1216(43):7241-8 [PMID: 19683245]
  5. J Asian Nat Prod Res. 2010 Aug;12(8):702-6 [PMID: 20706908]
  6. Bioorg Med Chem. 2007 May 15;15(10):3381-9 [PMID: 17391969]
  7. Braz J Med Biol Res. 2005 Jan;38(1):111-8 [PMID: 15665997]
  8. Biomedica. 2012 Jan-Mar;32(1):125-33 [PMID: 23235794]
  9. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Nov 1;875(1):136-41 [PMID: 18676186]
  10. Food Chem Toxicol. 2010 Jun;48(6):1734-40 [PMID: 20385194]
  11. ARYA Atheroscler. 2013 Jan;9(1):98-101 [PMID: 23696766]
  12. J Cosmet Dermatol. 2014 Jun;13(2):151-7 [PMID: 24910279]
  13. J Agric Food Chem. 2008 Jan 9;56(1):227-34 [PMID: 18078317]
  14. East Afr Med J. 1992 Apr;69(4):223-6 [PMID: 1644035]
  15. Acta Trop. 2013 Jul;127(1):33-7 [PMID: 23545130]
  16. J Agric Food Chem. 2012 May 2;60(17):4336-41 [PMID: 22500738]
  17. J Agric Food Chem. 2013 Sep 18;61(37):8773-82 [PMID: 24004007]
  18. Prog Neuropsychopharmacol Biol Psychiatry. 2010 May 30;34(4):605-9 [PMID: 20211673]
  19. Lett Appl Microbiol. 2008 Sep;47(3):167-73 [PMID: 19552780]
  20. Physiol Behav. 2000 Oct 1-15;71(1-2):83-6 [PMID: 11134689]
  21. Parasitol Res. 2012 Oct;111(4):1757-69 [PMID: 22797605]
  22. Asian Pac J Trop Biomed. 2012 Feb;2(2):152-5 [PMID: 23569887]
  23. Biomed Chromatogr. 2009 Mar;23(3):239-49 [PMID: 18823075]
  24. J Agric Food Chem. 2015 Jan 21;63(2):578-87 [PMID: 25539394]
  25. Pak J Pharm Sci. 2015 Jan;28(1):231-9 [PMID: 25553700]
  26. Analyst. 2005 May;130(5):772-8 [PMID: 15852150]
  27. Pak J Biol Sci. 2008 Jan 1;11(1):48-54 [PMID: 18819592]
  28. Theor Appl Genet. 2006 May;112(8):1519-31 [PMID: 16699791]
  29. Molecules. 2008 Jun 12;13(6):1333-44 [PMID: 18596659]
  30. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):291-7 [PMID: 17035106]
  31. Zhongguo Zhong Yao Za Zhi. 1995 Jul;20(7):397-8, 446 [PMID: 7576134]
  32. Molecules. 2007 Aug 03;12(8):1641-73 [PMID: 17960080]
  33. Molecules. 2009 May 25;14(5):1938-47 [PMID: 19471213]
  34. J Insect Sci. 2013;13:142 [PMID: 24766523]
  35. Life Sci. 2006 Dec 23;80(3):245-53 [PMID: 17046027]
  36. Biomed Chromatogr. 2005 Mar;19(2):138-48 [PMID: 15515108]
  37. Life Sci. 2012 Oct 5;91(11-12):429-439 [PMID: 22935404]
  38. J Sci Food Agric. 2011 Aug 15;91(10):1855-62 [PMID: 21480267]
  39. Guang Pu Xue Yu Guang Pu Fen Xi. 2009 Jan;29(1):259-62 [PMID: 19385253]
  40. Phytochem Anal. 2004 Sep-Oct;15(5):293-9 [PMID: 15508833]
  41. Br J Biomed Sci. 2009;66(4):180-5 [PMID: 20095125]
  42. Boll Chim Farm. 1996 Apr;135(4):263-6 [PMID: 8913055]
  43. J Agric Food Chem. 2004 Dec 1;52(24):7331-8 [PMID: 15563216]
  44. J Altern Complement Med. 2012 Aug;18(8):798-804 [PMID: 22849536]
  45. Rapid Commun Mass Spectrom. 2006;20(14):2151-64 [PMID: 16773675]
  46. Org Med Chem Lett. 2014 Jul 07;4:5 [PMID: 25024932]
  47. J Appl Microbiol. 2012 May;112(5):1020-33 [PMID: 22372962]
  48. Pest Manag Sci. 2005 Jun;61(6):597-604 [PMID: 15662650]
  49. Bioelectrochemistry. 2009 Sep;76(1-2):76-80 [PMID: 19447685]
  50. J Nat Prod. 1993 Sep;56(9):1627-9 [PMID: 8254356]
  51. Biofactors. 2007;30(2):129-38 [PMID: 18356584]
  52. Biomed Environ Sci. 2014 Oct;27(10):815-8 [PMID: 25341818]
  53. Phytother Res. 2009 Jul;23(7):948-54 [PMID: 19153985]
  54. J Sci Food Agric. 2011 Jan 15;91(1):142-51 [PMID: 20862741]
  55. Food Chem. 2014 Apr 15;149:244-52 [PMID: 24295703]
  56. Parasitol Res. 2009 Apr;104(5):1109-17 [PMID: 19050919]
  57. J Chromatogr A. 2003 May 23;998(1-2):229-33 [PMID: 12862387]
  58. Trends Genet. 2001 Sep;17(9):536-40 [PMID: 11525837]
  59. Parasitol Res. 2011 May;108(5):1099-109 [PMID: 21079994]
  60. J Agric Food Chem. 2009 Jun 24;57(12):5610-4 [PMID: 19453170]
  61. Boll Chim Farm. 2000 Sep-Oct;139(5):225-7 [PMID: 11213443]
  62. Mol Nutr Food Res. 2007 Dec;51(12):1478-84 [PMID: 17979096]
  63. Int J Appl Basic Med Res. 2014 Sep;4(Suppl 1):S20-2 [PMID: 25298937]
  64. Phytochem Anal. 2008 Sep-Oct;19(5):429-37 [PMID: 18435528]
  65. Eur J Nutr. 2006 Mar;45(3):152-8 [PMID: 16096701]
  66. Phytother Res. 2008 Jan;22(1):82-5 [PMID: 17726732]
  67. J Food Sci. 2012 Nov;77(11):C1156-61 [PMID: 23106968]
  68. J Sci Food Agric. 2010 Apr 15;90(5):870-6 [PMID: 20355124]
  69. Plant Foods Hum Nutr. 2014 Sep;69(3):255-60 [PMID: 24928688]
  70. Fitoterapia. 2006 Apr;77(3):151-5 [PMID: 16530345]
  71. J Med Food. 2009 Apr;12(2):298-303 [PMID: 19459729]
  72. Southeast Asian J Trop Med Public Health. 2011 Sep;42(5):1083-92 [PMID: 22299433]
  73. Nat Prod Commun. 2010 Mar;5(3):471-6 [PMID: 20420330]
  74. J Agric Food Chem. 2007 Jul 11;55(14):5761-7 [PMID: 17579430]
  75. Phytomedicine. 1996 Jan;2(3):221-7 [PMID: 23194620]
  76. J Chromatogr A. 2004 Aug 27;1047(2):313-7 [PMID: 15460264]
  77. Pak J Biol Sci. 2007 Apr 15;10(8):1151-60 [PMID: 19069909]
  78. J Parasitol Res. 2010;2010: [PMID: 20700425]
  79. Plant J. 2003 Dec;36(5):664-74 [PMID: 14617067]
  80. Foodborne Pathog Dis. 2009 Apr;6(3):387-94 [PMID: 19278342]
  81. Afr J Tradit Complement Altern Med. 2013 Nov 02;11(1):93-6 [PMID: 24653559]
  82. J Med Food. 2007 Mar;10(1):11-7 [PMID: 17472461]
  83. J Appl Microbiol. 2009 Apr;106(4):1343-9 [PMID: 19187138]
  84. J Agric Food Chem. 2000 Nov;48(11):5501-6 [PMID: 11087509]
  85. Int J Mol Sci. 2013 Dec 05;14(12):23736-50 [PMID: 24317433]
  86. Agric Biol Chem. 1991 Dec;55(12):2923-9 [PMID: 1368762]
  87. J Food Sci Technol. 2012 Dec;49(6):729-36 [PMID: 24293692]
  88. Nat Prod Res. 2015;29(23):2256-60 [PMID: 25588369]
  89. Pak J Biol Sci. 2009 Aug 1;12(15):1063-8 [PMID: 19943462]
  90. Fitoterapia. 2007 Sep;78(6):426-9 [PMID: 17628348]
  91. J Agric Food Chem. 2001 Feb;49(2):1035-41 [PMID: 11262068]
  92. J Food Sci. 2008 Aug;73(6):M264-7 [PMID: 19241555]
  93. Mol Nutr Food Res. 2009 Mar;53(3):398-406 [PMID: 19065586]
  94. Parasitol Res. 2012 May;110(5):1929-36 [PMID: 22127387]
  95. J Agric Food Chem. 2004 Dec 15;52(25):7586-92 [PMID: 15675808]
  96. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Aug;79(3):594-8 [PMID: 21536485]
  97. J Agric Food Chem. 2010 Oct 27;58(20):11119-29 [PMID: 20882960]
  98. Nat Prod Commun. 2010 Nov;5(11):1819-22 [PMID: 21213990]
  99. Am J Trop Med Hyg. 2001 Oct;65(4):304-8 [PMID: 11693874]
  100. J Agric Food Chem. 2008 Sep 10;56(17):7815-22 [PMID: 18683948]
  101. Electrophoresis. 2006 Feb;27(4):787-92 [PMID: 16411273]
  102. Talanta. 2009 Dec 15;80(2):749-53 [PMID: 19836547]
  103. Nat Prod Res. 2013 Mar;27(4-5):506-8 [PMID: 22799453]

MeSH Term

Biological Products
Citrus sinensis
Drug Discovery
Humans

Chemicals

Biological Products
Journal Article Review
Article has an altmetric score of 18

Word Cloud

Created with Highcharts 10.0.0sinensisnewdrugsnaturalsourceCitrusproductsbeneficialreviewchemistryactivitiesPresentlysearchresourcesgrowinginterestpharmaceuticalindustryNaturalsinceancienttimesPlantsgoodsecondarymetabolitesfoundpropertiespresentstudypharmacologyrevealstherapeuticpotentialCcompoundsimportanthumanhealthuseddevelopChemistryPharmacologyorangepharmacological

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