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Indian journal of surgical oncology
Jun, 2016;7 (2): 177-87.

Cytoreductive Surgery plus HIPEC for Peritoneal Metastases from Colorectal Cancer.

Aditi Bhatt, Diane Goéré
Author Information
  1. Aditi Bhatt: Department of Surgical Oncology, Fortis Hospital, 154/9 Bannerghatta road, Opposite IIM-Bangalore, Bangalore, -560076 India.
  2. Diane Goéré: Department of Surgical Oncology, Gustave Roussy, Cancer Campus, Villejuif, France.
PMID: 27065708 DOI: 10.1007/s13193-016-0499-z

Abstract

Occurring either synchronously or metachronously to the primary tumor, peritoneal metastases (PM) are diagnosed in 8 to 20 % of the patients with colorectal cancer (CRC). Prognosis of these patients appears to be worse than those with other sites of metastases. While systemic therapy has shown significant prolongation of survival in patients with stage IV colorectal cancer, the outcomes in the subset of patients with PM has been much inferior. Over the last 2 decades, cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) have been effective in substantially prolonging survival in patients with colorectal PM and have the potential to cure certain patients as well. This article reviews the current evidence for CRS and HIPEC to treat colorectal PM as well as future research going on in this form of locoregional treatment.

Keywords

Colorectal Cancer Cytoreductive surgery HIPEC Peritoneal Metastases

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