ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus.
Abdelmajid Zouhir: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia. zouheirabdelmajid@yahoo.fr. ORCID
Malek Taieb: Faculty of Sciences of Gabes, University of gabes, Gabès, Tunisia.
Mohamed Ashraf Lamine: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Ammar Cherif: Faculty of Sciences of Tunis, Université of El Manar , Tunis, Tunisia.
Taoufik Jridi: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Basma Mahjoubi: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Sarra Mbarek: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Ismail Fliss: Institut des Nutraceutiques et des Aliments Fonctionnels (INAF), Université Laval, Quebec, Canada.
Adel Nefzi: Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL, USA.
Khaled Sebei: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Jeannette Ben Hamida: Nutraceuticals and Functional Proteomics Potential of Biodiversity in Tunisia, University of Tunis ELMANAR, Tunis, Tunisia.
Staphylococcus aureus and methicillin-resistant S. aureus are major pathogens. The antimicrobial peptides and essential oils (EOs) display narrow- or broad-spectrum activity against bacteria including these strains. A centralized resource, such as a database, designed specifically for anti-S. aureus/anti-methicillin-resistant S. aureus antimicrobial peptides and EOs is therefore needed to facilitate the comprehensive investigation of their structure/activity associations and combinations. The database ANTISTAPHYBASE is created to facilitate access to important information on antimicrobial peptides and essential peptides against methicillin-resistant S. aureus and S. aureus. At the moment, the database contains 596 sequences of antimicrobial peptides produced by diverse organisms and 287 essential oil records. It permits a quick and easy search of peptides based on their activity as well as their general, physicochemical properties and literature data. These data are very useful to perform further bioinformatic or chemometric analysis and would certainly be useful for the development of new drugs for medical use. The ANTISTAPHYBASE database is freely available at: https://www.antistaphybase.com/ .
