Recruiting pregnant smokers from Text4baby for a randomized controlled trial of Quit4baby.

Leah Leavitt, Lorien Abroms, Pamela Johnson, Jennifer Schindler-Ruwisch, Jessica Bushar, Indira Singh, Sean D Cleary, Whitney McInvale, Monique Turner
Author Information
  1. Leah Leavitt: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA. Leah_leavitt@gwmail.gwu.edu. ORCID
  2. Lorien Abroms: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA.
  3. Pamela Johnson: Voxiva, Inc., 1820 N Fort Myer Dr, Suite 600, Arlington, VA, 22209, USA.
  4. Jennifer Schindler-Ruwisch: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA.
  5. Jessica Bushar: ZERO TO THREE, 1255 23rd Street, NW, Suite 350, Washington, DC, 20037, USA.
  6. Indira Singh: Voxiva, Inc., 1820 N Fort Myer Dr, Suite 600, Arlington, VA, 22209, USA.
  7. Sean D Cleary: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA.
  8. Whitney McInvale: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA.
  9. Monique Turner: Prevention and Community Health, The George Washington University Milken Institute School of Public Health, 950 New Hampshire Ave., 3rd Floor, Washington, DC, 20052, USA.

Abstract

Recruiting pregnant smokers into clinical trials is challenging since this population tends to be disadvantaged, the behavior is stigmatized, and the intervention window is limited. The purpose of this study is to test the feasibility and effectiveness of recruiting pregnant smokers into a smoking cessation trial by sending recruitment text messages to an existing subscriber list. Recruitment messages were sent to subscribers flagged as pregnant in Text4baby, a national text messaging program for pregnant women and mothers. Four recruitment messages were rotated to test the effectiveness of different emotional frames and a financial incentive. Study staff called subscribers who expressed interest to screen for eligibility and enroll eligible women. Between October 6, 2015 and February 2, 2016, 10,194 recruitment messages were sent to Text4baby subscribers flagged as pregnant, and 10.18% (1038) responded indicating interest. No significant increase in cancellation was observed compared to subscribers who received other ad hoc messages. Of respondents, 54.05% (561) were reached by phone for follow-up, and 21.97% (228) were found to be eligible. Among the eligible, 87% (199) pregnant smokers enrolled. The recruitment message with a pride emotional appeal had a significantly higher response (p = 0.02) compared to the recruitment message with no emotional appeal, but enrollment did not significantly differ between recruitment messages with different emotional appeals. The recruitment messages with a reference to financial incentive yielded higher response (p < 0.01) and enrollment (p = 0.03) compared to a recruitment message without. This study demonstrates success recruiting pregnant smokers using text message. Future studies should consider building on this approach for recruiting high-risk populations.

Keywords

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Grants

  1. R44 DA035017/NIDA NIH HHS
  2. R15 CA167586/NCI NIH HHS
  3. R01 CA201873/NCI NIH HHS
  4. K07 CA124579/NCI NIH HHS
  5. R34 DA037042/NIDA NIH HHS

MeSH Term

Adult
Emotions
Feasibility Studies
Female
Follow-Up Studies
Humans
Patient Selection
Pregnancy
Pregnancy Complications
Pregnant People
Reward
Smokers
Smoking
Smoking Cessation
Telephone
Text Messaging

Word Cloud

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