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Brain and behavior
01, 2017;7 (1): e00606.

Severe carotid artery stenosis evaluated by ultrasound is associated with post stroke vascular cognitive impairment.

Xuefeng Li, Xiangling Ma, Jing Lin, Xiangqin He, Feng Tian, Dongmei Kong
Author Information
  1. Xuefeng Li: Department of Ultrasonography Jining No.1 People's Hospital Jining Shandong China.
  2. Xiangling Ma: Department of Ultrasonography Jining No.1 People's Hospital Jining Shandong China.
  3. Jing Lin: Health Supervision Institute Zoucheng Municipal Health Bureau Zoucheng Shandong China.
  4. Xiangqin He: Department of Ultrasonography Jining No.1 People's Hospital Jining Shandong China.
  5. Feng Tian: Department of Neurology Jining No.1 People's Hospital Jining Shandong China.
  6. Dongmei Kong: Department of Ultrasonography Jining No.1 People's Hospital Jining Shandong China.
PMID: 28127524 DOI: 10.1002/brb3.606

Abstract

BACKGROUND: Acute ischemic stroke has been recognized as one key cause of vascular cognitive impairment (VCI). The purpose of this study was to evaluate the correlation between carotid artery stenosis and post VCI in acute ischemic stroke patients.
METHODS: In this study, B-mode ultrasound was applied to measure the degree of carotid artery stenosis. After 1 year, the stroke patients' cognitive function was assessed by the mini-mental state examination (MMSE) score. The relationship between the VCI and degree of carotid artery stenosis was evaluated by multivariate regression analysis.
RESULTS: VCI was observed in 136 (37.2%) of the 365 participants. High degree of carotid artery stenosis was significantly correlated with VCI ( < .01), and this correlation remained unchanged even adjustment for age, gender, education level, stroke features, and vascular risk factors.
CONCLUSIONS: These findings indicate that high-grade stenosis of carotid artery is positively correlated with post stroke VCI in patients with acute ischemic stroke. The evaluation of 1 year post stroke cognitive function may be a potential tool for screening stroke patients at risk of VCI.

Keywords

carotid artery stenosis mini‐mental state examination score stroke ultrasound vascular cognitive impairment

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MeSH Term

Aged
Aged, 80 and over
Brain Ischemia
Carotid Stenosis
Cognitive Dysfunction
Female
Follow-Up Studies
Humans
Male
Middle Aged
Severity of Illness Index
Stroke
Ultrasonography
Journal Article

Word Cloud

Created with Highcharts 10.0.0strokeVCIcarotidarterystenosiscognitivevascularpostischemicimpairmentpatientsultrasounddegreestudycorrelationacute1 yearfunctionstateexaminationscoreevaluatedcorrelatedriskBACKGROUND:AcuterecognizedonekeycausepurposeevaluateMETHODS:B-modeappliedmeasurepatients'assessedmini-mentalMMSErelationshipmultivariateregressionanalysisRESULTS:observed136372%365participantsHighsignificantly<01remainedunchangedevenadjustmentagegendereducationlevelfeaturesfactorsCONCLUSIONS:findingsindicatehigh-gradepositivelyevaluationmaypotentialtoolscreeningSevereassociatedmini‐mental

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