Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study.

Amin Daoulah, Amir Lotfi, Mushabab Al-Murayeh, Salem Al-Kaabi, Salem M Al-Faifi, Osama E Elkhateeb, Mohamed N Alama, Ahmad S Hersi, Ciaran M Dixon, Waleed Ahmed, Mohamed Al-Shehri, Ali Youssef, Ahmed Moustafa Elimam, Ayman S Abougalambou, Waheed Murad, Alawi A Alsheikh-Ali
Author Information
  1. Amin Daoulah: Section of Adult Cardiology, Cardiovascular Department, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia. ORCID
  2. Amir Lotfi: Division of Cardiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA, USA.
  3. Mushabab Al-Murayeh: Cardiovascular Department, Armed Forces Hospital, Southern Region, Khamis Mushayt, Saudi Arabia.
  4. Salem Al-Kaabi: Cardiovascular Department, Zayed Military Hospital, Abu Dhabi, UAE.
  5. Salem M Al-Faifi: Section of Pulmonology, Internal Medicine Department, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia.
  6. Osama E Elkhateeb: Cardiac Center, King Abdullah Medical City in Holy Capital, Makkah, Saudi Arabia. ORCID
  7. Mohamed N Alama: Cardiovascular Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
  8. Ahmad S Hersi: Cardiovascular Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
  9. Ciaran M Dixon: Emergency Department, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
  10. Waleed Ahmed: Section of Infectious Disease, Internal Medicine Department, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia.
  11. Mohamed Al-Shehri: Cardiovascular Department, Armed Forces Hospital, Southern Region, Khamis Mushayt, Saudi Arabia.
  12. Ali Youssef: Cardiovascular Department, Suez Canal University, Ismailia, Egypt.
  13. Ahmed Moustafa Elimam: Cardiovascular Department, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
  14. Ayman S Abougalambou: Cardiac Center, King Abdullah Medical City in Holy Capital, Makkah, Saudi Arabia.
  15. Waheed Murad: Cardiovascular Department, Zayed Military Hospital, Abu Dhabi, UAE.
  16. Alawi A Alsheikh-Ali: College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE; Institute of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, UAE.

Abstract

Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and the Middle East, but its association with CAD is not well defined. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period from April 1, 2013, to March 30, 2014. Of 1,068 enrolled patients, 687 were married men. Polygamy was reported in 32% of married men (1 wife: 68%, 2 wives: 19%, 3 wives: 10%, and 4 wives: 3%). When stratified by number of wives, significant baseline differences were observed in age, type of community (rural versus urban), prior coronary artery bypass grafting (CABG), and household income. After adjusting for baseline differences, there was a significant association between polygamy and CAD (adjusted OR 4.6 [95% CI 2.5, 8.3]), multivessel disease (MVD) (adjusted OR 2.6 [95% CI 1.8, 3.7]), and left main disease (LMD) (adjusted OR 3.5 [95% CI 2.1, 5.9]). Findings were consistent when the number of wives was analyzed as a continuous variable. In conclusion, among married men undergoing coronary angiography for clinical indications, polygamy is associated with the presence of significant CAD, MVD, and LMD.

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