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Frontiers in cellular and infection microbiology
2017;7 36.

Diversity and Co-infection with Other Tick Borne Pathogens in Ticks.

Cristian Raileanu, Sara Moutailler, Ionuţ Pavel, Daniela Porea, Andrei D Mihalca, Gheorghe Savuta, Muriel Vayssier-Taussat
Author Information
  1. Cristian Raileanu: INRA, UMR Bipar, INRA, Anses, ENVAMaisons-Alfort, France; Department of Public Health, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary MedicineIaşi, Romania.
  2. Sara Moutailler: INRA, UMR Bipar, INRA, Anses, ENVA Maisons-Alfort, France.
  3. Ionuţ Pavel: Department of Public Health, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Iaşi, Romania.
  4. Daniela Porea: Department of Public Health, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Iaşi, Romania.
  5. Andrei D Mihalca: Department of Parasitology and Parasitic Diseases, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Romania.
  6. Gheorghe Savuta: Department of Public Health, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Iaşi, Romania.
  7. Muriel Vayssier-Taussat: INRA, UMR Bipar, INRA, Anses, ENVA Maisons-Alfort, France.
PMID: 28261565 DOI: 10.3389/fcimb.2017.00036

Abstract

Identifying as the causative agent of Lyme disease in 1981 was a watershed moment in understanding the major impact that tick-borne zoonoses can have on public health worldwide, particularly in Europe and the USA. The medical importance of tick-borne diseases has long since been acknowledged, yet little is known regarding the occurrence of emerging tick-borne pathogens such as spp., spp., spp., " Neoehrlichia mikurensis", and tick-borne encephalitis virus in questing ticks in Romania, a gateway into Europe. The objective of our study was to identify the infection and co-infection rates of different genospecies along with other tick-borne pathogens in questing ticks collected from three geographically distinct areas in eastern Romania. We collected 557 questing adult and nymph ticks of three different species (534 , 19 , and 4 ) from three areas in Romania. We analyzed ticks individually for the presence of eight different genospecies with high-throughput real-time PCR. Ticks with were then tested for possible co-infections with spp., spp., " Neoehrlichia mikurensis", and tick-borne encephalitis virus. spp. was detected in ticks from all sampling areas, with global prevalence rates of 25.8%. All eight genospecies were detected in ticks: (14.8%), (8.8%), (5.1%), (4.9%), (0.9%), s.s (0.4%), and (0.2%). Regarding pathogen co-infection 64.5% of infected were positive for more than one pathogen. Associations between different genospecies were detected in 9.7% of ticks, and 6.9% of ticks tested positive for co-infection of spp. with other tick-borne pathogens. The most common association was between and (4.3%), followed by and (3.0%). The most frequent dual co-infections were between spp. and spp., (1.3%), and between spp. and " Neoehrlichia mikurensis" (1.3%). The diversity of tick-borne pathogens detected in this study and the frequency of co-infections should influence all infection risk evaluations following a tick bite.

Keywords

Borrelia Romania co-infection questing ticks tick-borne pathogens

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MeSH Term

Animals
Biodiversity
Borrelia
Borrelia Infections
Coinfection
Europe
Genotype
Geography
Humans
Ixodes
Lyme Disease
Tick Infestations
Tick-Borne Diseases
Zoonoses
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 13

Word Cloud

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