Renal failure caused by a partly calcified aortic aneurysm in a patient with dabigatran therapy: A case report.

Philipp Jud, Thomas Gary, Kurt Tiesenhausen, Rupert Portugaller, Gerald Hackl, Marianne Brodmann
Author Information
  1. Philipp Jud: Division of Angiology, Department of Internal Medicine Division of Vascular Surgery, Department of Surgery Division of Vascular and Interventional Radiology, Department of Radiology Division of Intensive Care Medicine, Department of Internal Medicine, Medical University of Graz, Graz, Austria.

Abstract

RATIONALE: Abdominal aortic aneurysms (AAAs) are mostly asymptomatic. If aortic aneurysms become symptomatic, complications include peripheral embolization, acute aortic occlusion, and aortic rupture. However, there are also unusual complications caused by aortic aneurysms.
PATIENT CONCERNS: An 87-old male with dabigatran therapy presented with newly developed melena and acute renal failure. Radiological imaging revealed an AAA with thrombotic and calcified deposits which affected the renal arteries.
DIAGNOSES: Gastrointestinal bleeding and hypercoagulation caused by renal failure which was triggered in turn due to an AAA.
INTERVENTIONS: Adapted antihypertensive therapy and initiation of simvastatin 40mg once daily as well as antiplatelet therapy with aspirin 50 mg once daily due to patient's refusal of any aneurysm intervention.
OUTCOME: Neither bleeding event nor aneurysm rupture occurred with the adapted antihypertensive therapy, simvastatin and aspirin.
LESSONS: Nonruptured AAAs can cause rare, unusual, and even life-threatening complications depending on their size and anatomical position.

References

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MeSH Term

Aged, 80 and over
Antithrombins
Aortic Aneurysm
Dabigatran
Diagnosis, Differential
Humans
Male
Melena
Renal Insufficiency
Vascular Calcification

Chemicals

Antithrombins
Dabigatran

Word Cloud

Created with Highcharts 10.0.0aortictherapyaneurysmscomplicationscausedrenalfailureaneurysmAAAsacuteruptureunusualdabigatranAAAcalcifiedbleedingdueantihypertensivesimvastatindailyaspirinRATIONALE:AbdominalmostlyasymptomaticbecomesymptomaticincludeperipheralembolizationocclusionHoweveralsoPATIENTCONCERNS:87-oldmalepresentednewlydevelopedmelenaRadiologicalimagingrevealedthromboticdepositsaffectedarteriesDIAGNOSES:GastrointestinalhypercoagulationtriggeredturnINTERVENTIONS:Adaptedinitiation40mgwellantiplatelet50 mgpatient'srefusalinterventionOUTCOME:NeithereventoccurredadaptedLESSONS:Nonrupturedcancauserareevenlife-threateningdependingsizeanatomicalpositionRenalpartlypatienttherapy:casereport

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