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Journal of autism and developmental disorders
08, 2017;47 (8): 2480-2501.

Childhood Predictors of Young Adult Social Functioning in 22q11.2 Deletion Syndrome.

Kayla E Wagner, Wendy R Kates, Wanda Fremont, Kevin M Antshel
Author Information
  1. Kayla E Wagner: Department of Psychology, Syracuse University, 430 Huntington Hall Syracuse, Syracuse, NY, 13244, USA.
  2. Wendy R Kates: Department of Psychiatry and Behavioral Sciences, SUNY-Upstate Medical University, Syracuse, NY, USA.
  3. Wanda Fremont: Department of Psychiatry and Behavioral Sciences, SUNY-Upstate Medical University, Syracuse, NY, USA.
  4. Kevin M Antshel: Department of Psychology, Syracuse University, 430 Huntington Hall Syracuse, Syracuse, NY, 13244, USA. kmantshe@syr.edu.
PMID: 28527096 DOI: 10.1007/s10803-017-3165-6

Abstract

The primary objectives of the current prospective longitudinal study were to (a) describe social functioning outcomes and (b) identify childhood predictors of social functioning in young adults with 22q11.2 deletion syndrome (22q11.2DS). Childhood predictors of young adult social functioning were examined. Family environment and parental stress in adolescence were investigated as potential mediators between childhood variables and adult social functioning. Parent rated childhood internalizing symptoms significantly predicted young adult social functioning in 22q11.2DS, even after controlling for concurrent positive symptoms of psychosis, and problem behaviors contributing to parenting stress in adolescence partially mediated this relationship. These findings highlight child internalizing symptoms and adolescent problem behaviors as potential targets for social functioning interventions in 22q11.2DS.

Keywords

22q11.2 Deletion Syndrome (22q11.2DS) Developmental delay Internalizing Longitudinal Social functioning

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Grants

  1. R01 MH064824/NIMH NIH HHS

MeSH Term

Adolescent
Child
DiGeorge Syndrome
Female
Humans
Male
Problem Behavior
Social Behavior
Journal Article
Article has an altmetric score of 3

Word Cloud

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