Fecal microbiota transplantation for recurrent clostridium difficile infection in children.

Becky Chen, Vishal Avinashi, Simon Dobson
Author Information
  1. Becky Chen: Division of Gastroenterology, Hepatology and Nutrition, British Columbia Children's Hospital, Vancouver, BC, Canada.
  2. Vishal Avinashi: Division of Gastroenterology, Hepatology and Nutrition, British Columbia Children's Hospital, Vancouver, BC, Canada. Electronic address: Vishal.Avinashi@cw.bc.ca.
  3. Simon Dobson: Division of Infectious Diseases, British Columbia Children's Hospital, Vancouver, BC, Canada.

Abstract

Fecal microbiota transplantation (FMT) is a relatively simple, promising treatment for recurrent Clostridium difficile infection. While there are a wide variety of approaches including mode of delivery, the results are nonetheless encouraging, even amongst younger children. Experience with FMT in the pediatric population is increasing, showing similar success compared to adults. This article will provide an overview of C. difficile infection along with review of the rationale, methods and complications of FMT including the current experience of FMT in children.

Keywords

MeSH Term

Adolescent
Child
Child, Preschool
Clostridium Infections
Fecal Microbiota Transplantation
Humans
Infant
Secondary Prevention
Treatment Outcome
Young Adult