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06 29, 2017;15 (1): 55.

Non-model model organisms.

James J Russell, Julie A Theriot, Pranidhi Sood, Wallace F Marshall, Laura F Landweber, Lillian Fritz-Laylin, Jessica K Polka, Snezhana Oliferenko, Therese Gerbich, Amy Gladfelter, James Umen, Magdalena Bezanilla, Madeline A Lancaster, Shuonan He, Matthew C Gibson, Bob Goldstein, Elly M Tanaka, Chi-Kuo Hu, Anne Brunet
Author Information
  1. James J Russell: Department of Biology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA.
  2. Julie A Theriot: Departments of Biochemistry and of Microbiology & Immunology, Howard Hughes Medical Institute Stanford University, Stanford, CA, 94305, USA. theriot@stanford.edu.
  3. Pranidhi Sood: Department of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA.
  4. Wallace F Marshall: Department of Biochemistry & Biophysics, University of California San Francisco, 600 16th St, San Francisco, CA, 94158, USA. Wallace.marshall@ucsf.edu.
  5. Laura F Landweber: Departments of Biochemistry & Molecular Biophysics and Biological Sciences, Columbia University, New York, NY, 10032, USA.
  6. Lillian Fritz-Laylin: Department of Biology, University of Massachusetts, Amherst, MA, 01003, USA.
  7. Jessica K Polka: Visiting Scholar, Whitehead Institute, 9 Cambridge Center, Cambridge, MA, 02142, USA.
  8. Snezhana Oliferenko: The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK.
  9. Therese Gerbich: 516 Fordham Hall, University of North Carolina Chapel Hill, Chapel Hill, NC, 27514, USA.
  10. Amy Gladfelter: 516 Fordham Hall, University of North Carolina Chapel Hill, Chapel Hill, NC, 27514, USA.
  11. James Umen: Donald Danforth Plant Science Center, 975 N. Warson Rd, St. Louis, MO, 63132, USA.
  12. Magdalena Bezanilla: Department of Biology, University of Massachusetts, Amherst, MA, 01003, USA.
  13. Madeline A Lancaster: MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, CB2 0QH, Cambridge, UK.
  14. Shuonan He: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA.
  15. Matthew C Gibson: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA.
  16. Bob Goldstein: Biology Department, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  17. Elly M Tanaka: Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus Vienna Biocenter 1, 1030, Vienna, Austria.
  18. Chi-Kuo Hu: Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
  19. Anne Brunet: Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
PMID: 28662661 DOI: 10.1186/s12915-017-0391-5

Abstract

Model organisms are widely used in research as accessible and convenient systems to study a particular area or question in biology. Traditionally only a handful of organisms have been widely studied, but modern research tools are enabling researchers to extend the set of model organisms to include less-studied and more unusual systems. This Forum highlights a range of 'non-model model organisms' as emerging systems for tackling questions across the whole spectrum of biology (and beyond), the opportunities and challenges, and the outlook for the future.

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Grants

  1. T32 CA009302/NCI NIH HHS
  2. R35 GM122555/NIGMS NIH HHS
  3. /Wellcome Trust
  4. R37 AI036929/NIAID NIH HHS
  5. DP1 AG044848/NIA NIH HHS
  6. R01 GM113602/NIGMS NIH HHS
  7. MC_UP_1201/9/Medical Research Council
  8. 103741/Z/14/Z/Wellcome Trust
  9. P50 GM107615/NIGMS NIH HHS

MeSH Term

Animals
Biology
Eukaryota
Models, Animal
Plants
Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't
Article has an altmetric score of 122

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