Disseminated cryptococcal infection in a patient who had kidney transplant: discrepancy between clinical symptoms and microbiological findings.
Suzan Dahdal, Robert Kalicki, Niklaus Von Steiger, Parham Sendi
Author Information
Suzan Dahdal: Department of Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Robert Kalicki: Department of Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Niklaus Von Steiger: Institute of Infectious Diseases, University of Bern, Bern, Switzerland.
Parham Sendi: Institute of Infectious Diseases, University of Bern, Bern, Switzerland.
A 29-year-old man complained of a 2-day history of frontal headache and new-onset fever but no other symptoms. Two months prior to admission, he underwent his third kidney transplantation. Clinical and laboratory examinations were unremarkable. Brain MRI showed a meningeal irritation consistent with viral meningitis. A diagnosis of cryptococcal meningitis and fungaemia was made after detection of a remarkably high and visible load of in the cerebrospinal fluid.