Disseminated cryptococcal infection in a patient who had kidney transplant: discrepancy between clinical symptoms and microbiological findings.

Suzan Dahdal, Robert Kalicki, Niklaus Von Steiger, Parham Sendi
Author Information
  1. Suzan Dahdal: Department of Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  2. Robert Kalicki: Department of Nephrology, Hypertension and Clinical Pharmacology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  3. Niklaus Von Steiger: Institute of Infectious Diseases, University of Bern, Bern, Switzerland.
  4. Parham Sendi: Institute of Infectious Diseases, University of Bern, Bern, Switzerland.

Abstract

A 29-year-old man complained of a 2-day history of frontal headache and new-onset fever but no other symptoms. Two months prior to admission, he underwent his third kidney transplantation. Clinical and laboratory examinations were unremarkable. Brain MRI showed a meningeal irritation consistent with viral meningitis. A diagnosis of cryptococcal meningitis and fungaemia was made after detection of a remarkably high and visible load of in the cerebrospinal fluid.

Keywords

References

  1. Emerg Infect Dis. 2001 May-Jun;7(3):375-81 [PMID: 11384512]
  2. J Infect Dis. 2007 Mar 1;195(5):756-64 [PMID: 17262720]
  3. Clin Kidney J. 2013 Apr;6(2):224-7 [PMID: 26019853]
  4. Arch Intern Med. 1976 Jun;136(6):670-7 [PMID: 776110]
  5. Clin Infect Dis. 2010 Apr 15;50(8):1101-11 [PMID: 20218876]
  6. Saudi J Kidney Dis Transpl. 2013 May;24(3):473-9 [PMID: 23640617]
  7. Infect Immun. 1981 Jun;32(3):1073-8 [PMID: 7251157]
  8. J Infect Dis. 1999 Feb;179(2):449-54 [PMID: 9878030]
  9. N Engl J Med. 2007 Dec 20;357(25):2601-14 [PMID: 18094380]

MeSH Term

Adult
Cryptococcus neoformans
Fever
Fungemia
Headache
Humans
Kidney Transplantation
Male
Meningitis, Cryptococcal
Postoperative Complications

Word Cloud

Created with Highcharts 10.0.0renalsymptomskidneymeningitiscryptococcal29-year-oldmancomplained2-dayhistoryfrontalheadachenew-onsetfeverTwomonthsprioradmissionunderwentthirdtransplantationClinicallaboratoryexaminationsunremarkableBrainMRIshowedmeningealirritationconsistentviraldiagnosisfungaemiamadedetectionremarkablyhighvisibleloadcerebrospinalfluidDisseminatedinfectionpatienttransplant:discrepancyclinicalmicrobiologicalfindingsdrugsmedicinesimmunologyinterventionmedicinesystem

Similar Articles

Cited By