OpenLB
Open Library of Bioscience
Advanced Search
Cold Spring Harbor perspectives in biology
07 02, 2018;10 (7):

The Cadherin Superfamily in Neural Circuit Assembly.

James D Jontes
Author Information
  1. James D Jontes: Department of Neuroscience, Ohio State University, Ohio 43210.
PMID: 28778868 DOI: 10.1101/cshperspect.a029306

Abstract

The cadherin superfamily comprises a large, diverse collection of cell surface receptors that are expressed in the nervous system throughout development and have been shown to be essential for the proper assembly of the vertebrate nervous system. As our knowledge of each family member has grown, it has become increasingly clear that the functions of various cadherin subfamilies are intertwined: they can be present in the same protein complexes, impinge on the same developmental processes, and influence the same signaling pathways. This interconnectedness may illustrate a central way in which core developmental events are controlled to bring about the robust and precise assembly of neural circuitry.

References

  1. Science. 2002 Jul 19;297(5580):365-9 [PMID: 12130776]
  2. Exp Cell Res. 1984 May;152(1):169-78 [PMID: 6370707]
  3. Mol Biol Cell. 2014 Mar;25(5):633-42 [PMID: 24371087]
  4. Dev Biol. 2009 Oct 1;334(1):72-83 [PMID: 19615992]
  5. J Neurosci. 1998 Sep 1;18(17):6892-904 [PMID: 9712659]
  6. Nat Rev Neurosci. 2009 Oct;10(10):724-35 [PMID: 19763105]
  7. J Neurosci. 2002 Sep 1;22(17):7617-26 [PMID: 12196585]
  8. Cell. 1980 Jun;20(2):363-71 [PMID: 7388946]
  9. Neuron. 2010 Apr 29;66(2):191-7 [PMID: 20434996]
  10. Dev Biol. 2005 Oct 15;286(2):601-17 [PMID: 16150435]
  11. Brain Res Mol Brain Res. 2005 Apr 4;134(2):294-308 [PMID: 15836925]
  12. Development. 2014 Apr;141(8):1671-82 [PMID: 24715457]
  13. Nat Neurosci. 2013 Feb;16(2):166-73 [PMID: 23292679]
  14. Nat Commun. 2016 Mar 04;7:10936 [PMID: 26939553]
  15. Neuron. 2007 Nov 8;56(3):456-71 [PMID: 17988630]
  16. Semin Cell Dev Biol. 2012 Feb;23(1):7-15 [PMID: 22044886]
  17. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13894-9 [PMID: 20616001]
  18. PLoS Genet. 2010 May 06;6(5):e1000936 [PMID: 20463883]
  19. Cereb Cortex. 2003 Jun;13(6):599-606 [PMID: 12764034]
  20. Proc Natl Acad Sci U S A. 1963 Oct;50:703-10 [PMID: 14077501]
  21. J Neurosci. 2012 Oct 31;32(44):15377-87 [PMID: 23115176]
  22. Nat Struct Biol. 1997 Jan;4(1):10-9 [PMID: 8989315]
  23. Science. 2006 Mar 17;311(5767):1609-12 [PMID: 16543460]
  24. EMBO J. 1986 Oct;5(10):2485-8 [PMID: 3780667]
  25. Nature. 2009 Mar 26;458(7237):501-4 [PMID: 19204731]
  26. Trends Neurosci. 2006 Apr;29(4):186-91 [PMID: 16490264]
  27. PLoS One. 2015 Oct 21;10(10):e0141290 [PMID: 26489017]
  28. Mol Cell Neurosci. 2008 May;38(1):66-79 [PMID: 18353676]
  29. Mol Psychiatry. 2017 Mar;22(3):364-374 [PMID: 27378146]
  30. Nat Rev Mol Cell Biol. 2005 Oct;6(10):777-88 [PMID: 16314867]
  31. Science. 1991 Jul 5;253(5015):85-7 [PMID: 2063209]
  32. Dev Biol. 1981 Oct 30;87(2):340-50 [PMID: 6793433]
  33. PLoS One. 2014 Nov 19;9(11):e113361 [PMID: 25409526]
  34. Curr Biol. 2014 Aug 18;24(16):1929-33 [PMID: 25127219]
  35. Curr Biol. 2011 Jan 11;21(1):79-86 [PMID: 21185191]
  36. Neuron. 2011 Aug 25;71(4):632-9 [PMID: 21867880]
  37. Neuron. 1996 Nov;17(5):837-48 [PMID: 8938117]
  38. Mol Cell Neurosci. 2004 Dec;27(4):509-21 [PMID: 15555928]
  39. Cell. 2014 Jan 16;156(1-2):195-207 [PMID: 24439376]
  40. J Cell Biol. 2015 Nov 23;211(4):807-14 [PMID: 26598617]
  41. Differentiation. 1983;24(2):140-4 [PMID: 6884616]
  42. Neuron. 2012 Apr 26;74(2):314-30 [PMID: 22542185]
  43. Dev Cell. 2014 Sep 29;30(6):673-87 [PMID: 25199687]
  44. J Cell Biol. 2010 Nov 29;191(5):1029-41 [PMID: 21115806]
  45. J Biol Chem. 1999 Jul 2;274(27):19473-1979 [PMID: 10383464]
  46. Cell. 2014 Aug 14;158(4):793-807 [PMID: 25126785]
  47. Physiol Rev. 2012 Apr;92(2):597-634 [PMID: 22535893]
  48. J Cell Biol. 2011 Sep 5;194(5):737-50 [PMID: 21875946]
  49. Nat Rev Neurosci. 2001 Dec;2(12):899-909 [PMID: 11733797]
  50. Development. 2003 Jun;130(11):2479-94 [PMID: 12702661]
  51. J Cell Biol. 1977 Nov;75(2 Pt 1):464-74 [PMID: 264120]
  52. Dev Dyn. 2007 Feb;236(2):534-43 [PMID: 17131403]
  53. Neuron. 2003 Nov 13;40(4):719-31 [PMID: 14622577]
  54. J Neurosci. 1998 Jul 15;18(14):5415-25 [PMID: 9651223]
  55. Mol Cell Neurosci. 2000 Jun;15(6):534-46 [PMID: 10860580]
  56. Nature. 2012 May 02;486(7401):118-21 [PMID: 22678292]
  57. J Neurosci. 2009 Apr 29;29(17):5435-42 [PMID: 19403811]
  58. Cell. 1995 Aug 11;82(3):371-81 [PMID: 7634327]
  59. J Neurosci. 2008 Jan 2;28(1):100-5 [PMID: 18171927]
  60. Nat Neurosci. 2004 Apr;7(4):357-63 [PMID: 15034585]
  61. J Cell Biol. 2011 Dec 26;195(7):1115-21 [PMID: 22184198]
  62. Dev Dyn. 2005 Jun;233(2):528-39 [PMID: 15844200]
  63. Dev Biol. 2006 Jul 1;295(1):52-66 [PMID: 16631155]
  64. Hippocampus. 2008;18(4):349-63 [PMID: 18064706]
  65. Neuron. 2003 Aug 28;39(5):749-65 [PMID: 12948443]
  66. J Neurosci. 2006 Nov 29;26(48):12620-30 [PMID: 17135424]
  67. Mol Cell Neurosci. 1998 Jul;11(4):183-93 [PMID: 9675050]
  68. Mol Cell Neurosci. 2009 Mar;40(3):390-400 [PMID: 19162191]
  69. Annu Rev Neurosci. 2009;32:149-84 [PMID: 19555289]
  70. Science. 1978 Nov 10;202(4368):639-41 [PMID: 309179]
  71. Cell. 1995 Aug 11;82(3):359-70 [PMID: 7634326]
  72. Sci Rep. 2016 May 31;6:26765 [PMID: 27240640]
  73. Oncol Rep. 2015 Aug;34(2):747-54 [PMID: 26081897]
  74. Neuroscience. 2003;117(3):593-614 [PMID: 12617965]
  75. Science. 1996 Nov 15;274(5290):1133-8 [PMID: 8895456]
  76. Cereb Cortex. 2016 Jul;26(7):3323-34 [PMID: 27170656]
  77. Prog Neurobiol. 2000 Aug;61(6):611-48 [PMID: 10775799]
  78. Nature. 2016 Apr 21;532(7599):370-4 [PMID: 27018655]
  79. Dev Biol. 2007 Apr 1;304(1):22-33 [PMID: 17222817]
  80. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2996-3004 [PMID: 25002511]
  81. Neuron. 2013 Jun 5;78(5):839-54 [PMID: 23684785]
  82. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17663-8 [PMID: 23045641]
  83. J Neurosci. 2015 Oct 28;35(43):14517-32 [PMID: 26511243]
  84. Science. 1997 May 30;276(5317):1428-31 [PMID: 9162013]
  85. Mol Biol Evol. 2011 Jan;28(1):647-57 [PMID: 20817718]
  86. Dev Biol. 2009 Apr 1;328(1):66-77 [PMID: 19389371]
  87. J Neurosci. 1999 Feb 1;19(3):995-1005 [PMID: 9920663]
  88. Science. 2008 May 16;320(5878):946-9 [PMID: 18487195]
  89. Curr Opin Neurobiol. 2006 Oct;16(5):562-70 [PMID: 16962767]
  90. Cell. 2014 Aug 28;158(5):1045-1059 [PMID: 25171406]
  91. Oncotarget. 2016 Aug 9;7(32):51720-51732 [PMID: 27351130]
  92. Cell Rep. 2014 Oct 9;9(1):311-323 [PMID: 25284782]
  93. PLoS Biol. 2004 Nov;2(11):e329 [PMID: 15514700]
  94. Science. 2011 Nov 4;334(6056):618-23 [PMID: 22053041]
  95. Development. 2002 Jul;129(14):3281-94 [PMID: 12091300]
  96. Neuron. 2002 Jul 3;35(1):77-89 [PMID: 12123610]
  97. J Neurosci. 2009 Jul 22;29(29):9137-47 [PMID: 19625505]
  98. J Cell Biol. 2008 Jul 28;182(2):395-410 [PMID: 18644894]
  99. Cell. 2012 Dec 21;151(7):1581-94 [PMID: 23260144]
  100. J Cell Biol. 2009 Jun 15;185(6):959-67 [PMID: 19506035]
  101. J Neurosci. 2003 Mar 15;23(6):2294-305 [PMID: 12657688]
  102. J Mol Neurosci. 2014;54(2):199-210 [PMID: 24647733]
  103. Development. 2001 Apr;128(8):1253-64 [PMID: 11262227]
  104. J Neurosci. 2004 Oct 13;24(41):9027-34 [PMID: 15483121]
  105. Neuron. 1996 Sep;17(3):423-34 [PMID: 8816706]
  106. Neuroscience. 1999 Mar;90(3):985-1000 [PMID: 10218798]
  107. Neuron. 2011 Aug 25;71(4):640-55 [PMID: 21867881]
  108. Genes Dev. 2011 Dec 1;25(23):2453-64 [PMID: 22085726]
  109. Dev Biol. 1998 Dec 15;204(2):317-26 [PMID: 9882473]

Grants

  1. R01 EY027003/NEI NIH HHS

MeSH Term

Animals
Cadherins
Cell Adhesion
Cell Movement
Gene Expression Regulation
Humans
Neurogenesis
Neurons

Chemicals

Cadherins
Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Review

Word Cloud

Created with Highcharts 10.0.0cadherinnervoussystemassemblydevelopmentalsuperfamilycompriseslargediversecollectioncellsurfacereceptorsexpressedthroughoutdevelopmentshownessentialpropervertebrateknowledgefamilymembergrownbecomeincreasinglyclearfunctionsvarioussubfamiliesintertwined:canpresentproteincomplexesimpingeprocessesinfluencesignalingpathwaysinterconnectednessmayillustratecentralwaycoreeventscontrolledbringrobustpreciseneuralcircuitryCadherinSuperfamilyNeuralCircuitAssembly

Similar Articles

Cited By