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Environmental science and pollution research international
Jan, 2018;25 (3): 2588-2593.

Malathion-induced spermatozoal oxidative damage and alterations in sperm quality of endangered trout Salmo coruhensis.

Mehmet Kocabaş, Filiz Kutluyer, Fulya Benzer, Mine Erişir
Author Information
  1. Mehmet Kocabaş: Department of Wildlife Ecology & Management, Karadeniz Technical University Faculty of Forestry, 61080, Trabzon, Turkey.
  2. Filiz Kutluyer: Fisheries Faculty, Munzur University, 62000, Tunceli, Turkey. filizkutluyer@hotmail.com.
  3. Fulya Benzer: Faculty of Engineering, Department of Food Engineering, Munzur University, 62000, Tunceli, Turkey.
  4. Mine Erişir: Faculty of Veterinary, Department of Basic Sciences, Fırat University, Elazığ, Turkey.
PMID: 29128945 DOI: 10.1007/s11356-017-0700-0

Abstract

The use of pesticides has been increased along with increasing the farming activities and has caused environmental impacts deleteriously. In particular, non-target organisms including fish can be affected by toxic effects of pesticides. Therefore, the impacts of malathion (MTN) on oxidative stress and sperm quality were investigated in vitro. The MTN concentrations used on this study were 0 (control), 75, 100, and 125 μg/L. Lipid peroxidation (MDA), non-enzymatic (GSH), and enzymatic (SOD, GSH-Px, and CAT) activities in spermatozoa were examined for determination of oxidative stress status. Our findings showed that motility rate and period of sperm cells significantly decreased with exposure to MTN. Biochemical assays revealed that CAT activity and levels of MDA, GSH increased in spermatozoa based on concentration while activity of GSH-Px and SOD decreased. Consequently, spermatozoa were highly sensitive to MTN exposure. MTN has disruptive effects on sperm quality and caused to oxidative stress in spermatozoa.

Keywords

Endangered trout Malathion Oxidative stress parameters Salmo coruhensis Sperm cell

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MeSH Term

Animals
Dose-Response Relationship, Drug
Endangered Species
Malathion
Male
Models, Theoretical
Oxidative Stress
Sperm Motility
Spermatozoa
Trout
Water Pollutants, Chemical

Chemicals

Water Pollutants, Chemical
Malathion
Journal Article

Word Cloud

Created with Highcharts 10.0.0MTNoxidativestressspermspermatozoaqualitypesticidesincreasedactivitiescausedimpactseffectsMDAGSHSODGSH-PxCATdecreasedexposureactivitytroutSalmocoruhensisusealongincreasingfarmingenvironmentaldeleteriouslyparticularnon-targetorganismsincludingfishcanaffectedtoxicThereforemalathioninvestigatedvitroconcentrationsusedstudy0control75100125 μg/LLipidperoxidationnon-enzymaticenzymaticexamineddeterminationstatusfindingsshowedmotilityrateperiodcellssignificantlyBiochemicalassaysrevealedlevelsbasedconcentrationConsequentlyhighlysensitivedisruptiveMalathion-inducedspermatozoaldamagealterationsendangeredEndangeredMalathionOxidativeparametersSpermcell

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