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01 23, 2018;10 (2):

Vaccinia virus in Feces and Urine of Wild Rodents from São Paulo State, Brazil.

Marina G Peres, Thais S Bacchiega, Camila M Appolinário, Acácia F Vicente, Mateus S R Mioni, Bruna L D Ribeiro, Clóvis R S Fonseca, Vanessa C Pelícia, Fernando Ferreira, Jonatas S Abrahão, Jane Megid
Author Information
  1. Marina G Peres: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. marinageavet@yahoo.com.br.
  2. Thais S Bacchiega: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. tatabacch@hotmail.com.
  3. Camila M Appolinário: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. camilaapp.vet@gmail.com.
  4. Acácia F Vicente: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. acaciavicente@hotmail.com.
  5. Mateus S R Mioni: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. mateusmioni@yahoo.com.br.
  6. Bruna L D Ribeiro: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. brunadevider@gmail.com.
  7. Clóvis R S Fonseca: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. crsfonseca2@yahoo.com.br.
  8. Vanessa C Pelícia: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. vcpelicia@yahoo.com.br.
  9. Fernando Ferreira: Faculdade de Medicina Veterinária e Zootecnia, USP-Universidade de São Paulo, São Paulo CEP 05508-270, Brazil. fernando@vps.fmvz.usp.br.
  10. Jonatas S Abrahão: Instituto de Ciências Biológicas, UFMG-Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil. jonatas.abrahao@gmail.com.
  11. Jane Megid: Faculdade de Medicina Veterinária e Zootecnia, UNESP-Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil. jane@fmvz.unesp.br. ORCID
PMID: 29360742 DOI: 10.3390/v10020051

Abstract

The origin of (VACV) outbreaks in Brazil remains unknown, but since the isolation of VACV in mice during a zoonotic outbreak affecting cattle and milkers, peridomestic rodents have been suggested to be a link between cows and wild animals. Considering that experimentally infected mice eliminate viral particles in their feces, we investigated the presence of VACV in the feces and urine of wild rodents that were captured in the forest areas surrounding milking farms in the central west region of São Paulo State. For the first time, this work reports the detection of VACV by PCR in the feces of naturally infected and and in the urine of which raises important questions about the spread of VACV by rodent feces and its potential to induce clinical infections in cows.

Keywords

PCR Vaccinia virus epidemiology public health transmission wild animals

References

  1. Emerg Infect Dis. 2012 Jan;18(1):189-91 [PMID: 22260819]
  2. Emerg Infect Dis. 2013 Dec;19(12):2017-20 [PMID: 24274374]
  3. Emerg Infect Dis. 2005 Dec;11(12):1935-8 [PMID: 16485483]
  4. Emerg Infect Dis. 2015 Apr;21(4):695-8 [PMID: 25811411]
  5. Emerg Infect Dis. 2009 May;15(5):781-4 [PMID: 19402968]
  6. Am J Trop Med Hyg. 2013 Dec;89(6):1142-5 [PMID: 24166043]
  7. J Gen Virol. 2008 Dec;89(Pt 12):2986-91 [PMID: 19008383]
  8. J Med Virol. 2010 Apr;82(4):692-9 [PMID: 20166167]
  9. PLoS One. 2009 Oct 19;4(10):e7428 [PMID: 19838293]
  10. Diagn Microbiol Infect Dis. 2007 Jan;57(1):39-46 [PMID: 16949244]
  11. Emerg Infect Dis. 2009 May;15(5):777-80 [PMID: 19402967]
  12. Virology. 2000 Nov 25;277(2):439-49 [PMID: 11080491]
  13. Arch Virol. 2013 Dec;158(12):2433-41 [PMID: 23760628]
  14. Vet Microbiol. 2010 Jan 27;140(3-4):229-36 [PMID: 19828265]
  15. Emerg Infect Dis. 2010 Jun;16(6):976-9 [PMID: 20507750]
  16. Virol J. 2009 Sep 11;6:140 [PMID: 19747382]
  17. Emerg Infect Dis. 2016 Feb;22(2):271-3 [PMID: 26812352]
  18. Arch Virol. 2009;154(9):1551-3 [PMID: 19710997]
  19. Vector Borne Zoonotic Dis. 2012 Jan;12(1):61-4 [PMID: 21923268]
  20. Am J Trop Med Hyg. 2008 Nov;79(5):647-51 [PMID: 18981497]
  21. Res Vet Sci. 2013 Oct;95(2):752-7 [PMID: 23747141]

MeSH Term

Animal Diseases
Animals
Animals, Wild
Brazil
Computational Biology
DNA, Viral
Disease Outbreaks
Farms
Feces
Forests
Geography, Medical
Phylogeny
Polymerase Chain Reaction
Rodentia
Sequence Analysis, DNA
Vaccinia
Vaccinia virus
Virus Shedding

Chemicals

DNA, Viral
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 1

Word Cloud

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