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Annals of clinical microbiology and antimicrobials
Feb 03, 2018;17 (1): 2.

Application of antimicrobial drugs in perioperative surgical incision.

Xu Yang, Xurao Xiao, Lefeng Wang, Yue Ao, Yapeng Song, Huabing Wang, Huanan Wang
Author Information
  1. Xu Yang: Department of Hematology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China.
  2. Xurao Xiao: College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.
  3. Lefeng Wang: College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.
  4. Yue Ao: College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.
  5. Yapeng Song: College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, China.
  6. Huabing Wang: College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. wanghb@zju.edu.cn.
  7. Huanan Wang: College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. hnwang@zju.edu.cn.
PMID: 29397046 DOI: 10.1186/s12941-018-0254-0

Abstract

infection in surgical incision often results in poor wound healing, and one of the main factors for wound infection is the use of antimicrobial agents. Rational use of antibiotics is one of the key factors to prevent incision infection in general surgery. The number of current clinical studies on antibiotic use before and during surgery is greater than that of systematic studies on antibiotic use after surgery. For the rational use of antibiotics and improvement of wound healing rate, researchers around the world have gradually focused on the use of antibiotics after surgery. Despite the familiarity on the concept of "rational use of antibiotics", few clear and systematic studies were conducted to elucidate the effect of different antibiotics on wound healing. Therefore, this review focuses on the use of different types of antimicrobial agents in surgical wounds.

Keywords

Antibacterial drugs Antibiotic Incision infection Surgical operation

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Grants

  1. 31602118/National Natural Science Foundation of China

MeSH Term

Anti-Bacterial Agents
Anti-Infective Agents
Antibiotic Prophylaxis
Humans
Surgical Wound
Surgical Wound Infection
Wound Healing

Chemicals

Anti-Bacterial Agents
Anti-Infective Agents
Journal Article Review
Article has an altmetric score of 2

Word Cloud

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