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Current heart failure reports
04, 2018;15 (2): 106-115.

Fill in the Gaps of Secondary Mitral Regurgitation: a Continuum Challenge From Pathophysiology to Prognosis.

Riccardo M Inciardi, Andrea Rossi, Giovanni Benfari, Mariantonietta Cicoira
Author Information
  1. Riccardo M Inciardi: Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
  2. Andrea Rossi: Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy. andrea9rossi@gmail.com.
  3. Giovanni Benfari: Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
  4. Mariantonietta Cicoira: Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy.
PMID: 29480349 DOI: 10.1007/s11897-018-0379-7

Abstract

PURPOSE OF REVIEW: Mitral regurgitation (MR) is one of the most frequent valvular heart diseases encountered in clinical practice. In contrast to primary MR, less is still known about the pathophysiology, diagnosis, and prognosis of secondary MR. The purpose of this report is to provide a review, upon the last knowledge reported in the literature, on the role and management of secondary MR in clinical practice.
RECENT FINDINGS: Recent data highlight secondary MR not as a single pathological entity but as a wide spectrum of interconnected conditions which portend poor outcome. Although the role of secondary MR on clinical outcome is debated, recent available data suggest an independent association of MR with prognosis. Nevertheless, available treatment did not show a clear benefit after MR correction. Further studies are needed to better categorize and assess secondary MR beyond schematic classification. A management approach should be tailored upon each clinical context of presentation.

Keywords

Echocardiography LV function LV remodeling Pathophysiology Secondary mitral regurgitation

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MeSH Term

Echocardiography
Heart Failure
Humans
Mitral Valve
Mitral Valve Insufficiency
Prognosis
Severity of Illness Index
Ventricular Function, Left
Ventricular Remodeling
Journal Article Review

Word Cloud

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