PharmGKB summary: atazanavir pathway, pharmacokinetics/pharmacodynamics.

Maria Alvarellos, Chantal Guillemette, Russ B Altman, Teri E Klein
Author Information
  1. Maria Alvarellos: Departments of Biomedical Data Science.
  2. Chantal Guillemette: Faculty of Pharmacy, University Hospital Center of Quebec (CHU), Laval University, Quebec City, Quebec, Canada.
  3. Russ B Altman: Genetics.
  4. Teri E Klein: Departments of Biomedical Data Science.

Abstract

No abstract text available.

References

  1. Pharmacogenomics. 2007 Mar;8(3):227-35 [PMID: 17324111]
  2. J Acquir Immune Defic Syndr. 2013 May 1;63(1):59-66 [PMID: 23392467]
  3. Clin Infect Dis. 2010 Jul 1;51(1):101-6 [PMID: 20504240]
  4. Clin Pharmacol Ther. 2016 Apr;99(4):363-9 [PMID: 26417955]
  5. Clin Infect Dis. 2012 Nov;55(9):1270-2 [PMID: 22820540]
  6. PLoS One. 2015 Sep 11;10 (9):e0137660 [PMID: 26360703]
  7. Mol Pharm. 2013 Aug 5;10 (8):3067-75 [PMID: 23750830]
  8. HIV Clin Trials. 2015 May-Jun;16(3):89-99 [PMID: 25979186]
  9. Pharmacogenet Genomics. 2017 May;27(5):201-209 [PMID: 28277330]
  10. Hepatology. 2006 Nov;44(5):1324-32 [PMID: 17058217]
  11. J Antimicrob Chemother. 2015 Nov;70(11):3096-9 [PMID: 26174719]
  12. J Infect Dis. 2005 Oct 15;192(8):1381-6 [PMID: 16170755]
  13. Adv Pharmacol. 2013;67:317-58 [PMID: 23886005]
  14. J Clin Pharmacol. 2017 Feb;57(2):235-246 [PMID: 27432796]
  15. Ann Hum Genet. 2011 Mar;75(2):236-46 [PMID: 21309756]
  16. Pharmacogenet Genomics. 2014 Mar;24(3):177-83 [PMID: 24492252]
  17. J Mass Spectrom. 2013 Jun;48(6):640-50 [PMID: 23722954]
  18. Pharmacogenet Genomics. 2011 Mar;21(3):152-61 [PMID: 20216335]
  19. J Acquir Immune Defic Syndr. 2009 Nov 1;52(3):431-2 [PMID: 19858926]
  20. Clin Infect Dis. 2014 Feb;58(4):555-63 [PMID: 24253247]
  21. J Antimicrob Chemother. 2010 Jan;65(1):129-37 [PMID: 19897506]
  22. J Antimicrob Chemother. 2009 Nov;64(5):1071-9 [PMID: 19710077]
  23. AIDS. 2015 Sep 10;29(14 ):1775-83 [PMID: 26372383]
  24. Pharm Res. 2014 Sep;31(9):2404-19 [PMID: 24595498]
  25. Top Antivir Med. 2017 Dec/Jan;24(4):132-133 [PMID: 28208121]
  26. Antivir Ther. 2015;20(1):57-64 [PMID: 24992294]
  27. J Antimicrob Chemother. 2014 Dec;69(12):3320-8 [PMID: 25151207]
  28. Xenobiotica. 2010 Mar;40(3):163-76 [PMID: 20102298]
  29. Infect Dis Clin North Am. 2014 Sep;28(3):371-402 [PMID: 25151562]
  30. Clin Infect Dis. 2012 Nov;55(9):1262-9 [PMID: 22820542]
  31. Lancet. 2008 Aug 23;372(9639):646-55 [PMID: 18722869]
  32. J Infect Dis. 2006 Sep 15;194 Suppl 1:S51-8 [PMID: 16921473]
  33. Pharmacogenet Genomics. 2018 Jan;28(1):1-6 [PMID: 29117017]
  34. Drugs. 2012 Jun 18;72(9):1161-73 [PMID: 22646049]
  35. Pharmacotherapy. 2004 Dec;24(12):1732-47 [PMID: 15585441]
  36. Br J Clin Pharmacol. 2011 Dec;72(6):940-7 [PMID: 21649692]
  37. J Antimicrob Chemother. 2012 Sep;67(9):2236-42 [PMID: 22661571]
  38. J Antimicrob Chemother. 2014 Nov;69(11):3061-6 [PMID: 24997317]
  39. Drug Metab Dispos. 2009 Sep;37(9):1826-40 [PMID: 19546238]
  40. J Infect Dis. 2013 Feb 1;207(3):420-5 [PMID: 23148286]
  41. Pediatr Res. 2016 Mar;79(3):378-86 [PMID: 26595536]
  42. Antimicrob Agents Chemother. 2011 Sep;55(9):4290-4 [PMID: 21670182]
  43. HIV AIDS (Auckl). 2015 Oct 27;7:251-64 [PMID: 26604826]
  44. Clin Infect Dis. 2006 Jan 15;42(2):291-5 [PMID: 16355344]
  45. Infect Dis Clin North Am. 2014 Sep;28(3):421-38 [PMID: 25151564]
  46. HIV Med. 2014 May;15(5):301-10 [PMID: 24314017]
  47. Open Forum Infect Dis. 2015 Jul 01;2(3):ofv085 [PMID: 26180834]
  48. J Microbiol Immunol Infect. 2017 Dec;50(6):789-797 [PMID: 26857335]
  49. Pharm Res. 2013 Apr;30(4):1050-64 [PMID: 23224979]
  50. J Antimicrob Chemother. 2016 Jun;71(6):1609-18 [PMID: 26892777]
  51. Clin Pharmacokinet. 2005;44(10):1035-50 [PMID: 16176117]
  52. Clin Infect Dis. 2008 Nov 1;47(9):1222-5 [PMID: 18831695]
  53. J Antimicrob Chemother. 2010 Aug;65(8):1672-80 [PMID: 20551216]
  54. AIDS. 2007 May 31;21(9):1215-8 [PMID: 17502736]
  55. Pharmacogenomics. 2014 Jul;15(10 ):1281-6 [PMID: 25155930]
  56. PLoS One. 2013 Oct 10;8(10):e77268 [PMID: 24130871]
  57. J Med Chem. 2012 May 24;55(10 ):4740-63 [PMID: 22541068]
  58. PLoS One. 2013 Jul 16;8(7):e69845 [PMID: 23875004]
  59. Drug Metab Dispos. 2011 Mar;39(3):394-401 [PMID: 21148252]
  60. Drug Metab Dispos. 2011 Mar;39(3):522-7 [PMID: 21148251]
  61. J Infect Dis. 2011 Jan 15;203(2):246-57 [PMID: 21288825]
  62. Antimicrob Agents Chemother. 2008 Feb;52(2):631-7 [PMID: 18025112]
  63. Eur J Clin Pharmacol. 2007 Oct;63(10):935-40 [PMID: 17665183]
  64. J Acquir Immune Defic Syndr. 2013 Jan 1;62(1):60-6 [PMID: 23011396]
  65. Antimicrob Agents Chemother. 2010 Dec;54(12 ):5242-50 [PMID: 20921307]
  66. J Antimicrob Chemother. 2014 Dec;69(12):3300-10 [PMID: 25159623]
  67. J Antimicrob Chemother. 2014 May;69(5):1385-9 [PMID: 24379301]
  68. J Int AIDS Soc. 2014 Nov 02;17(4 Suppl 3):19560 [PMID: 25394067]
  69. Pharmacogenet Genomics. 2014 Apr;24(4):195-203 [PMID: 24557078]
  70. Pharmacogenet Genomics. 2010 Feb;20(2):112-20 [PMID: 20051929]
  71. J Acquir Immune Defic Syndr. 2011 Apr 15;56(5):412-9 [PMID: 21283017]
  72. AIDS. 2007 Jan 2;21(1):41-6 [PMID: 17148966]
  73. AIDS Res Hum Retroviruses. 2012 Oct;28(10):1227-34 [PMID: 22394315]
  74. J Acquir Immune Defic Syndr. 2015 May 1;69(1):e36-7 [PMID: 25622064]

Grants

  1. R24 GM061374/NIGMS NIH HHS
  2. MOP#42392/Canadian Institute of Health Research

MeSH Term

ATP Binding Cassette Transporter, Subfamily B
Atazanavir Sulfate
Drug Synergism
Glucuronosyltransferase
HIV Infections
HIV Protease Inhibitors
Humans
Liver-Specific Organic Anion Transporter 1
Pharmacogenetics
Pregnane X Receptor
Ritonavir

Chemicals

ABCB1 protein, human
ATP Binding Cassette Transporter, Subfamily B
HIV Protease Inhibitors
Liver-Specific Organic Anion Transporter 1
NR1I2 protein, human
Pregnane X Receptor
SLCO1B1 protein, human
Atazanavir Sulfate
UGT1A1 enzyme
Glucuronosyltransferase
Ritonavir

Word Cloud

Created with Highcharts 10.0.0PharmGKBsummary:atazanavirpathwaypharmacokinetics/pharmacodynamics

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