Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams.
Giovanni Traverso, Ameya R Kirtane, Carl M Schoellhammer, Robert Langer
Author Information
Giovanni Traverso: Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. ORCID
Ameya R Kirtane: Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Carl M Schoellhammer: Suono Bio, Inc., 700 Main St., North, Cambridge, MA, 02139, USA. ORCID
Robert Langer: Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. ORCID
The void between drug discovery and successful translation to humans is vast. In order to develop effective solutions, convergence of a multidisciplinary team with a range of expertise is required. In this Essay, examples of successful sustained delivery systems for antimalarials and antiretrovirals, as well as to the gastrointestinal tract are discussed.