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In vivo (Athens, Greece)
2018 May-Jun;32 (3): 611-623.

Meta-analysis of Robot-assisted Laparoscopic Surgery for Rectal Cancer.

Hiroshi Ohtani, Kiyoshi Maeda, Shinya Nomura, Osamu Shinto, Yoko Mizuyama, Hiroji Nakagawa, Hisashi Nagahara, Masatsune Shibutani, Tatsunari Fukuoka, Ryosuke Amano, Kosei Hirakawa, Masaichi Ohira
Author Information
  1. Hiroshi Ohtani: Department of Surgery, Ohno Memorial Hospital, Osaka, Japan m5051923@msic.med.osaka-cu.ac.jp.
  2. Kiyoshi Maeda: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  3. Shinya Nomura: Department of Surgery, Ohno Memorial Hospital, Osaka, Japan.
  4. Osamu Shinto: Department of Surgery, Ohno Memorial Hospital, Osaka, Japan.
  5. Yoko Mizuyama: Department of Surgery, Ohno Memorial Hospital, Osaka, Japan.
  6. Hiroji Nakagawa: Department of Surgery, Ohno Memorial Hospital, Osaka, Japan.
  7. Hisashi Nagahara: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  8. Masatsune Shibutani: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  9. Tatsunari Fukuoka: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  10. Ryosuke Amano: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  11. Kosei Hirakawa: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
  12. Masaichi Ohira: Department of Surgical Oncology, Osaka City University Graduate School of Medicine, Osaka, Japan.
PMID: 29695568 DOI: 10.21873/invivo.11283

Abstract

BACKGROUND/AIM: A meta-analysis was conducted to evaluate and compare the short- and long-term outcomes of robot-assisted (RAS) and conventional laparoscopic surgery (LAS) for rectal cancer.
MATERIALS AND METHODS: We searched MEDLINE for relevant papers published between 2010 and December 2017 by using specific search terms. We analyzed outcomes over short- and long-term periods.
RESULTS: We identified 23 papers reporting results that compared RAS for rectal cancer with LAS. Our meta-analysis included 4,348 patients with rectal cancer; 2,068 had undergone RAS, and 2,280 had undergone LAS. In the short- and long-term period, 27 and 7 outcome variables were examined, respectively. RAS for rectal cancer was significantly associated with a greater operative time and a lower conversion rate to open surgery in the short-term, and results in almost similar outcomes in the long-term, compared to LAS.
CONCLUSION: RAS may be an acceptable surgical treatment option compared to LAS for rectal cancer.

Keywords

Rectal cancer laparoscopic surgery meta-analysis robot-assisted surgery

References

  1. N Engl J Med. 2004 May 13;350(20):2050-9 [PMID: 15141043]
  2. Ann Surg Oncol. 2009 Jun;16(6):1480-7 [PMID: 19290486]
  3. ANZ J Surg. 2003 Sep;73(9):712-6 [PMID: 12956787]
  4. Surg Endosc. 2010 Nov;24(11):2888-94 [PMID: 20526623]
  5. Surg Endosc. 2013 Nov;27(11):4157-63 [PMID: 23708725]
  6. Surg Laparosc Endosc. 1991 Sep;1(3):144-50 [PMID: 1688289]
  7. Surg Endosc. 2013 Jan;27(1):48-55 [PMID: 22752275]
  8. Surg Endosc. 2013 Jun;27(6):1887-95 [PMID: 23292566]
  9. Medicine (Baltimore). 2015 Mar;94(11):e522 [PMID: 25789947]
  10. Dis Colon Rectum. 2002 Dec;45(12):1689-94; discussion 1695-6 [PMID: 12473897]
  11. Lancet. 2005 May 14-20;365(9472):1718-26 [PMID: 15894098]
  12. Int J Colorectal Dis. 2016 Sep;31(9):1639-48 [PMID: 27475091]
  13. J Gastrointest Surg. 2011 Aug;15(8):1375-85 [PMID: 21557014]
  14. Int J Colorectal Dis. 2013 Dec;28(12):1689-98 [PMID: 23948968]
  15. Dis Colon Rectum. 2011 Feb;54(2):151-6 [PMID: 21228661]
  16. Int J Med Robot. 2014 Sep;10(3):300-5 [PMID: 24692203]
  17. World J Surg. 2016 Apr;40(4):1010-6 [PMID: 26552907]
  18. Medicine (Baltimore). 2014 Nov;93(25):e109 [PMID: 25437022]
  19. J Korean Soc Coloproctol. 2010 Dec;26(6):377-87 [PMID: 21221237]
  20. Br J Surg. 2013 Jan;100(1):75-82 [PMID: 23132548]
  21. Surg Endosc. 2011 Feb;25(2):521-5 [PMID: 20607559]
  22. J Cancer. 2012;3:49-57 [PMID: 22315650]
  23. Ann Surg. 2017 May;265(5):960-968 [PMID: 27232247]
  24. Cancer Res Treat. 2016 Jan;48(1):225-31 [PMID: 25779367]
  25. World J Surg. 2012 Nov;36(11):2722-9 [PMID: 22855217]
  26. Surg Endosc. 2009 Dec;23(12):2831-5 [PMID: 19440794]
  27. J Clin Epidemiol. 2009 Oct;62(10):e1-34 [PMID: 19631507]
  28. Am J Surg. 2013 Oct;206(4):509-17 [PMID: 23809672]
  29. Int J Colorectal Dis. 2016 Jun;31(6):1179-87 [PMID: 27080161]
  30. Dis Colon Rectum. 2009 Apr;52(4):558-66 [PMID: 19404053]
  31. BMC Med Res Methodol. 2005 Apr 20;5:13 [PMID: 15840177]
  32. JSLS. 2009 Apr-Jun;13(2):176-83 [PMID: 19660212]
  33. Acta Chir Iugosl. 2010;57(3):29-35 [PMID: 21066980]
  34. Surg Endosc. 2011 Jan;25(1):240-8 [PMID: 20552367]
  35. Ann Surg. 2013 Jan;257(1):95-101 [PMID: 23059496]

MeSH Term

Blood Loss, Surgical
Chemoradiotherapy
Clinical Trials as Topic
Humans
Laparoscopy
Neoadjuvant Therapy
Operative Time
Postoperative Complications
Rectal Neoplasms
Robotic Surgical Procedures
Treatment Outcome
Journal Article Meta-Analysis
Article has an altmetric score of 3

Word Cloud

Created with Highcharts 10.0.0cancerRASLASrectallong-termsurgerymeta-analysisshort-outcomescomparedrobot-assistedlaparoscopicpapersresults2undergoneRectalBACKGROUND/AIM:conductedevaluatecompareconventionalMATERIALSANDMETHODS:searchedMEDLINErelevantpublished2010December2017usingspecificsearchtermsanalyzedperiodsRESULTS:identified23reportingincluded4348patients068280period277outcomevariablesexaminedrespectivelysignificantlyassociatedgreateroperativetimelowerconversionrateopenshort-termalmostsimilarCONCLUSION:mayacceptablesurgicaltreatmentoptionMeta-analysisRobot-assistedLaparoscopicSurgeryCancer

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