Oncofertility in the setting of advanced cervical cancer - A case report.
Catherine Gordon, Joseph C Carmichael, Krishnansu S Tewari
Author Information
Catherine Gordon: Department of Obstetrics & Gynecology, University of California, Irvine 333 City Blvd, West, Suite 1400, Orange, CA 92868, United States.
Joseph C Carmichael: Division of Colon and Rectal Surgery, Department of Surgery, University of California, Irvine 333 City Blvd, West, Suite 850, Orange, CA 92868, United States.
Krishnansu S Tewari: Department of Obstetrics & Gynecology, University of California, Irvine 333 City Blvd, West, Suite 1400, Orange, CA 92868, United States.
OBJECTIVE: To consider fertility options in women with advanced cervical cancer. DESIGN: Case report. SETTING: Large tertiary care center. PATIENT: A 30-year-old nulligravida woman diagnosed with FIGO Stage IB squamous cell carcinoma of the cervix that had metastasized to a pelvic lymph node. INTERVENTIONS: Robotic radical trachelectomy with pelvic lymphadenectomy and cerclage placement, followed by ovarian stimulation with oocyte retrieval and in vitro fertilization. Subsequent therapy included adjuvant chemoradiation and embryo transfer to a surrogate mother. MAIN OUTCOME MEASURES: Cervical cancer remission, live birth from surrogate pregnancy. RESULTS: 33-year-old woman in her third year of remission from advanced cervical cancer with healthy twin girls. CONCLUSIONS: Fertility options may exist for patients even in the setting of metastatic cervical cancer. Early involvement of a reproductive endocrinologist is imperative. This case emphasizes the importance of cross-specialty communication.
