OpenLB
Open Library of Bioscience
Advanced Search
Cerebral cortex (New York, N.Y. : 1991)
08 01, 2018;28 (8): 3035-3045.

The Ventral Anterior Temporal Lobe has a Necessary Role in Exception Word Reading.

Taiji Ueno, Lotte Meteyard, Paul Hoffman, Kou Murayama
Author Information
  1. Taiji Ueno: School of Psychology & Clinical Language Sciences, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, UK.
  2. Lotte Meteyard: School of Psychology & Clinical Language Sciences, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, UK.
  3. Paul Hoffman: Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), Department of Psychology, University of Edinburgh, Edinburgh, UK.
  4. Kou Murayama: School of Psychology & Clinical Language Sciences, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, UK.
PMID: 29878073 DOI: 10.1093/cercor/bhy131

Abstract

An influential account of reading holds that words with exceptional spelling-to-sound correspondences (e.g., PINT) are read via activation of their lexical-semantic representations, supported by the anterior temporal lobe (ATL). This account has been inconclusive because it is based on neuropsychological evidence, in which lesion-deficit relationships are difficult to localize precisely, and functional neuroimaging data, which is spatially precise but cannot demonstrate whether the ATL activity is necessary for exception word reading. To address these issues, we used a technique with good spatial specificity-repetitive transcranial magnetic stimulation (rTMS)-to demonstrate a necessary role of ATL in exception word reading. Following rTMS to left ventral ATL, healthy Japanese adults made more regularization errors in reading Japanese exception words. We successfully simulated these results in a computational model in which exception word reading was underpinned by semantic activations. The ATL is critically and selectively involved in reading exception words.

References

  1. Cereb Cortex. 2015 Oct;25(10):3802-17 [PMID: 25491206]
  2. Brain. 2016 May;139(Pt 5):1517-26 [PMID: 26966139]
  3. Brain. 2009 Jan;132(Pt 1):71-86 [PMID: 19022856]
  4. Front Psychol. 2012 May 28;3:161 [PMID: 22654779]
  5. J Neurosci. 2006 Jul 12;26(28):7328-36 [PMID: 16837579]
  6. Psychol Rev. 2007 Apr;114(2):316-39 [PMID: 17500629]
  7. Psychol Bull. 2013 Jul;139(4):766-91 [PMID: 23046391]
  8. J Cogn Neurosci. 2010 Apr;22(4):739-50 [PMID: 19302001]
  9. Psychol Rev. 2004 Jul;111(3):662-720 [PMID: 15250780]
  10. Neurology. 2011 Mar 15;76(11):1006-14 [PMID: 21325651]
  11. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):E3719-28 [PMID: 26124121]
  12. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):20137-41 [PMID: 18056637]
  13. Ment Retard Dev Disabil Res Rev. 2000;6(3):207-13 [PMID: 10982498]
  14. Neuroimage. 2003 Oct;20(2):693-712 [PMID: 14568445]
  15. Nat Rev Neurosci. 2007 Dec;8(12):976-87 [PMID: 18026167]
  16. J Psycholinguist Res. 1973 Jul;2(3):175-99 [PMID: 4795473]
  17. Cogn Neuropsychol. 2005 Sep;22(6):695-717 [PMID: 21038273]
  18. Neuropsychologia. 2009 Mar;47(4):1061-8 [PMID: 19162051]
  19. Clin Neurophysiol. 2009 Dec;120(12):2008-2039 [PMID: 19833552]
  20. Cortex. 2016 Nov;84:90-100 [PMID: 27721080]
  21. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8162-7 [PMID: 27325763]
  22. Cereb Cortex. 2011 May;21(5):1066-75 [PMID: 20851853]
  23. Ann Neurol. 2004 Dec;56(6):836-46 [PMID: 15514975]
  24. Nat Rev Neurosci. 2000 Oct;1(1):73-9 [PMID: 11252771]
  25. Neuron. 2011 Oct 20;72(2):385-96 [PMID: 22017995]
  26. J Magn Reson Imaging. 2006 Jun;23(6):816-26 [PMID: 16649208]
  27. J Cogn Neurosci. 2010 Jun;22(6):1083-94 [PMID: 19583477]
  28. J Cogn Neurosci. 2015 Jun;27(6):1259-74 [PMID: 25603024]
  29. J Neurosci. 2010 Aug 18;30(33):11057-61 [PMID: 20720112]
  30. Neuroimage. 2012 May 1;60(4):2000-7 [PMID: 22361167]
  31. Psychol Rev. 1996 Jan;103(1):56-115 [PMID: 8650300]
  32. Nat Rev Neurosci. 2007 May;8(5):393-402 [PMID: 17431404]
  33. Front Hum Neurosci. 2012 May 01;6:120 [PMID: 22557962]
  34. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12279-12284 [PMID: 29087311]
  35. Neurobiol Aging. 2009 Jan;30(1):103-11 [PMID: 17604879]
  36. Psychol Rev. 2001 Jan;108(1):204-56 [PMID: 11212628]
  37. Cogn Neuropsychol. 2011 Mar;28(2):65-108 [PMID: 22122115]
  38. Neuroimage. 2008 Sep 1;42(3):1226-36 [PMID: 18639469]
  39. Cogn Neuropsychol. 2008 Mar;25(2):136-64 [PMID: 18568816]
  40. J Cogn Neurosci. 2015 Mar;27(3):593-604 [PMID: 25244114]
  41. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16494-9 [PMID: 20807747]
  42. Brain. 2010 Nov;133(11):3256-68 [PMID: 20952377]
  43. Cereb Cortex. 2010 Aug;20(8):1799-815 [PMID: 19920057]
  44. Brain Lang. 2014 Jun;133:1-13 [PMID: 24735993]
  45. Cereb Cortex. 2010 Nov;20(11):2728-38 [PMID: 20190005]
  46. J Cogn Neurosci. 2006 Feb;18(2):169-83 [PMID: 16494679]
  47. Cogn Sci. 2017 May;41 Suppl 6:1288-1317 [PMID: 27322895]
  48. Psychol Rev. 2010 Jan;117(1):256-71; discussion 271-2 [PMID: 20063972]
  49. Brain Lang. 2014 Jul;134:44-67 [PMID: 24815949]
  50. J Cogn Neurosci. 2011 Oct;23(10):3121-31 [PMID: 21391767]

Grants

  1. MR/K026992/1/Medical Research Council
  2. /Biotechnology and Biological Sciences Research Council

MeSH Term

Adult
Brain Mapping
Computer Simulation
Female
Functional Laterality
Humans
Magnetic Resonance Imaging
Male
Models, Neurological
Random Allocation
Reaction Time
Reading
Semantics
Temporal Lobe
Transcranial Magnetic Stimulation
United Kingdom
Verbal Learning
Vocabulary
Journal Article Research Support, Non-U.S. Gov't
Article has an altmetric score of 7

Word Cloud

Created with Highcharts 10.0.0readingATLexceptionwordswordaccountdemonstratenecessaryrTMSJapaneseinfluentialholdsexceptionalspelling-to-soundcorrespondencesegPINTreadviaactivationlexical-semanticrepresentationssupportedanteriortemporallobeinconclusivebasedneuropsychologicalevidencelesion-deficitrelationshipsdifficultlocalizepreciselyfunctionalneuroimagingdataspatiallyprecisewhetheractivityaddressissuesusedtechniquegoodspatialspecificity-repetitivetranscranialmagneticstimulation-toroleFollowingleftventralhealthyadultsmaderegularizationerrorssuccessfullysimulatedresultscomputationalmodelunderpinnedsemanticactivationscriticallyselectivelyinvolvedVentralAnteriorTemporalLobeNecessaryRoleExceptionWordReading

Similar Articles

Cited By