- Samantha E Yohn: Department of Pharmacology , Vanderbilt University , Nashville , Tennessee 37232 , United States.
- P Jeffrey Conn: Department of Pharmacology , Vanderbilt University , Nashville , Tennessee 37232 , United States.
While the negative symptoms comprise one of the cardinal symptom domains of schizophrenia, there are numerous deficits that are included in this category of symptoms. Therefore, when modeling negative symptoms preclinically, it is important to consider which symptom is being modeled by a specific assay and to try to gain an understanding of the translational value of the findings. It is hoped that enhancing the translational value of animal models will allow for better treatment outcomes for the negative symptoms of schizophrenia in the future.