Effects of Carbohydrate Mouth Rinse on Cycling Time Trial Performance: A Systematic Review and Meta-Analysis.

Cayque Brietzke, Paulo Estevão Franco-Alvarenga, Hélio José Coelho-Júnior, Rodrigo Silveira, Ricardo Yukio Asano, Flávio Oliveira Pires
Author Information
  1. Cayque Brietzke: Exercise Psychophysiology Research Group, School of Arts, Sciences and Humanities, University of São Paulo, 1000 Arlindo Béttio Avenue, Ermelino Matarazzo, São Paulo, SP, 03828-000, Brazil. ORCID
  2. Paulo Estevão Franco-Alvarenga: Exercise Psychophysiology Research Group, School of Arts, Sciences and Humanities, University of São Paulo, 1000 Arlindo Béttio Avenue, Ermelino Matarazzo, São Paulo, SP, 03828-000, Brazil. ORCID
  3. Hélio José Coelho-Júnior: Applied Kinesiology Laboratory, University of Campinas, 701 Érico Veríssimo Avenue, Barão Geraldo, Campinas, SP, 13.083-851, Brazil. ORCID
  4. Rodrigo Silveira: Exercise Psychophysiology Research Group, School of Arts, Sciences and Humanities, University of São Paulo, 1000 Arlindo Béttio Avenue, Ermelino Matarazzo, São Paulo, SP, 03828-000, Brazil. ORCID
  5. Ricardo Yukio Asano: Exercise Psychophysiology Research Group, School of Arts, Sciences and Humanities, University of São Paulo, 1000 Arlindo Béttio Avenue, Ermelino Matarazzo, São Paulo, SP, 03828-000, Brazil. ORCID
  6. Flávio Oliveira Pires: Exercise Psychophysiology Research Group, School of Arts, Sciences and Humanities, University of São Paulo, 1000 Arlindo Béttio Avenue, Ermelino Matarazzo, São Paulo, SP, 03828-000, Brazil. piresfo@usp.br. ORCID

Abstract

BACKGROUND: Despite the growing number of studies reporting carbohydrate mouth rinse effects on endurance performance, no systematic and meta-analysis review has been conducted to elucidate the level of evidence of carbohydrate mouth rinse effects on cycling trial performance such as time-, work-, and distance-based trials.
OBJECTIVES: The objective of this study were to establish the effect of a carbohydrate mouth rinse on cycling performance outcomes such as mean power output and time to complete a trial, together with the risk of bias in the cycling-carbohydrate mouth rinse literature.
METHODS: We systematically reviewed randomized placebo-controlled trials that assessed carbohydrate mouth rinse effects on mean power output and time to complete the trial. A random-effects meta-analysis assessed the standardized mean difference between carbohydrate and placebo mouth rinses.
RESULTS: Thirteen studies (16 trials) were qualitatively (systematic review) and quantitatively (meta-analysis) analyzed with regard to mean power output (n = 175) and time to complete the trial (n = 151). Overall, the reviewed studies showed a low risk of bias and homogeneous results for mean power output (I = 0%) and time to complete the trial (I = 0%). When compared with placebo, the carbohydrate mouth rinse improved mean power output (standardized mean difference = 0.25; 95% confidence interval 0.04-0.46; p = 0.02), but not the time to complete the trial (standardized mean difference = - 0.13; 95% confidence interval - 0.36 to 0.10; p = 0.25).
CONCLUSION: The present systematic and meta-analytic review supports the notion that a carbohydrate mouth rinse has the potential to increase mean power output in cycling trials, despite showing no superiority over placebo in improving time to complete the trials.

References

  1. Curr Sports Med Rep. 2013 Jul-Aug;12(4):222-7 [PMID: 23851408]
  2. J Appl Physiol (1985). 1986 Jul;61(1):165-72 [PMID: 3525502]
  3. J Strength Cond Res. 2014 Sep;28(9):2513-20 [PMID: 24584047]
  4. J Sports Med Phys Fitness. 2019 Jan;59(1):1-5 [PMID: 29148629]
  5. Med Sci Sports Exerc. 2011 Mar;43(3):468-75 [PMID: 20689457]
  6. Curr Opin Clin Nutr Metab Care. 2010 Jul;13(4):447-51 [PMID: 20453646]
  7. Med Sci Sports Exerc. 2004 Dec;36(12):2107-11 [PMID: 15570147]
  8. Sports Med. 2011 Jun 1;41(6):449-61 [PMID: 21615187]
  9. J Physiol. 1995 Nov 15;489 ( Pt 1):243-50 [PMID: 8583408]
  10. BMJ. 2003 Sep 6;327(7414):557-60 [PMID: 12958120]
  11. J Physiol. 2009 Apr 15;587(Pt 8):1779-94 [PMID: 19237430]
  12. Nutrients. 2016 Mar 09;8(3):49 [PMID: 27005660]
  13. BMJ. 2015 Mar 16;350:h1435 [PMID: 25778910]
  14. Med Sci Sports Exerc. 2016 Sep;48(9):1810-20 [PMID: 27128664]
  15. J Strength Cond Res. 2017 Jun;31(6):1737-1743 [PMID: 28538327]
  16. J Strength Cond Res. 2015 Aug;29(8):2316-25 [PMID: 25734778]
  17. Nutrients. 2013 Dec 19;6(1):1-10 [PMID: 24451304]
  18. J Sports Sci Med. 2018 Mar 01;17(1):145-152 [PMID: 29535588]
  19. Ann Intern Med. 2009 Aug 18;151(4):W65-94 [PMID: 19622512]
  20. Eur J Sport Sci. 2016 Nov;16(8):1073-8 [PMID: 27339107]
  21. J Int Soc Sports Nutr. 2016 Jul 11;13:27 [PMID: 27408608]
  22. Appl Physiol Nutr Metab. 2013 Feb;38(2):134-9 [PMID: 23438223]
  23. Scand J Med Sci Sports. 2010 Feb;20(1):105-11 [PMID: 19000099]
  24. Scand J Med Sci Sports. 2013 Dec;23(6):e361-72 [PMID: 23909650]
  25. Nutrients. 2018 Mar 12;10(3): [PMID: 29534507]
  26. Int J Sport Nutr Exerc Metab. 2009 Aug;19(4):400-9 [PMID: 19827464]
  27. Int J Sport Nutr Exerc Metab. 2015 Dec;25(6):576-83 [PMID: 26132895]
  28. Med Sci Sports Exerc. 1984 Jun;16(3):219-22 [PMID: 6748917]
  29. Front Physiol. 2016 Jul 05;7:253 [PMID: 27458381]
  30. Brain Res. 2010 Sep 2;1350:151-8 [PMID: 20388497]
  31. Nutrients. 2016 May 09;8(5): [PMID: 27171108]
  32. J Neurosci. 2015 Jan 28;35(4):1773-80 [PMID: 25632150]
  33. Int J Sport Nutr Exerc Metab. 2017 Feb;27(1):25-31 [PMID: 27616732]
  34. BMJ. 2011 Oct 18;343:d5928 [PMID: 22008217]
  35. J Appl Physiol (1985). 2016 Feb 15;120(4):464-6 [PMID: 26404617]
  36. Clin Physiol Funct Imaging. 2017 Jan;37(1):17-22 [PMID: 26302885]
  37. J Acad Nutr Diet. 2016 Mar;116(3):501-528 [PMID: 26920240]
  38. J Sports Sci Med. 2018 May 14;17(2):181-187 [PMID: 29769818]

Grants

  1. #2016/16496-3/São Paulo Research Foundation (FAPESP)

MeSH Term

Athletic Performance
Bicycling
Dietary Carbohydrates
Exercise Test
Humans
Mouthwashes
Performance-Enhancing Substances
Randomized Controlled Trials as Topic

Chemicals

Dietary Carbohydrates
Mouthwashes
Performance-Enhancing Substances

Word Cloud

Created with Highcharts 10.0.0meanmouthcarbohydraterinsetrialpoweroutputtimecompletetrialsstudieseffectsperformancesystematicmeta-analysisreviewcyclingstandardizedplaceboriskbiasreviewedassessedI = 0%2595%confidenceinterval0p = 0BACKGROUND:Despitegrowingnumberreportingenduranceconductedelucidatelevelevidencetime-work-distance-basedOBJECTIVES:objectivestudyestablisheffectoutcomestogethercycling-carbohydrateliteratureMETHODS:systematicallyrandomizedplacebo-controlledrandom-effectsdifferencerinsesRESULTS:Thirteen16qualitativelyquantitativelyanalyzedregardn = 175n = 151Overallshowedlowhomogeneousresultscomparedimproveddifference = 004-04602difference = - 013- 03610CONCLUSION:presentmeta-analyticsupportsnotionpotentialincreasedespiteshowingsuperiorityimprovingEffectsCarbohydrateMouthRinseCyclingTimeTrialPerformance:SystematicReviewMeta-Analysis

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