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British journal of clinical pharmacology
03, 2019;85 (3): 492-500.

Antibiotic allergy labels in hospitalized and critically ill adults: A review of current impacts of inaccurate labelling.

Rebekah Moran, Misha Devchand, Olivia Smibert, Jason A Trubiano
Author Information
  1. Rebekah Moran: Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia. ORCID
  2. Misha Devchand: Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia.
  3. Olivia Smibert: Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  4. Jason A Trubiano: Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia. ORCID
PMID: 30521088 DOI: 10.1111/bcp.13830

Abstract

Antibiotic allergy labels (AALs) are reported by approximately 20% of hospitalized patients, yet over 85% will be negative on formal allergy testing. Hospitalized patients with an AAL have inferior patient outcomes, increased colonization with multidrug-resistant organisms and frequently receive inappropriate antimicrobials. Hospitalized populations have been well studied but, to date, the impact of AALs on patients with critical illness remains less well defined. We review the prevalence and impact of AALs on hospitalized patients, including those in in critical care.

Keywords

acute care antimicrobial allergy antimicrobial stewardship penicillin allergy skin testing

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MeSH Term

Adult
Anti-Bacterial Agents
Antimicrobial Stewardship
Critical Care
Critical Illness
Drug Hypersensitivity
Guideline Adherence
Hospitalization
Humans
Intensive Care Units
Practice Guidelines as Topic
Prevalence
Self Report
Skin Tests

Chemicals

Anti-Bacterial Agents
Journal Article Research Support, Non-U.S. Gov't Review
Article has an altmetric score of 2

Word Cloud

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