Early rapid weight gain among formula-fed infants: Impact of formula type and maternal feeding styles.

J A Mennella, M A Papas, A R Reiter, V A Stallings, J C Trabulsi
Author Information
  1. J A Mennella: Monell Chemical Senses Center, Philadelphia, Pennsylvania. ORCID
  2. M A Papas: Christiana Care Health System Value Institute, Newark, Delaware.
  3. A R Reiter: Monell Chemical Senses Center, Philadelphia, Pennsylvania.
  4. V A Stallings: Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  5. J C Trabulsi: Department of Behavioral Health and Nutrition, University of Delaware College of Health and Sciences, Newark, Delaware.

Abstract

BACKGROUND: What and how infants are fed are considered important determinants for the risk factor of early rapid gain weight.
OBJECTIVES: We conducted secondary analyses on data from a randomized clinical trial, wherein infants randomized to feed cow milk formula had double the incidence of early rapid weight gain than those fed extensively hydrolyzed protein formula, to determine whether maternal feeding styles had independent effects or interactive effects with infant formula type on early rapid weight gain.
METHODS: Anthropometry and feeding patterning (number of daily formula feeds) were measured monthly, and maternal feeding styles were measured at 0.5, 3.5, and 4.5 months. Longitudinal models were fitted using generalized estimating equations and separate logistic models conducted.
RESULTS: The treatment groups did not differ in formula feeding patterning or in maternal feeding styles, which were stable across the first 4.5 months. Feeding styles had no significant effects on early rapid weight gain and did not interact with formula group. However, type of infant formula had a direct and independent impact on early rapid weight gain (P = 0.003).
CONCLUSIONS: The type of infant formula had a differential impact on early rapid weight gain independent of maternal feeding style, highlighting the self-regulatory capabilities of infants.

Keywords

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Grants

  1. R01 HD072307/NICHD NIH HHS
  2. R03 HD094908/NICHD NIH HHS
  3. R03HD09408/NICHD NIH HHS
  4. R01HD072307/NICHD NIH HHS

MeSH Term

Adult
Animals
Anthropometry
Cattle
Feeding Behavior
Female
Humans
Infant Formula
Infant, Newborn
Male
Weight Gain

Word Cloud

Created with Highcharts 10.0.0formulafeedingrapidgainweightearlymaternalstylesinfanttypeinfantsindependenteffectspatterningfedconductedrandomizedmeasured545 monthsmodelsimpactBACKGROUND:consideredimportantdeterminantsriskfactorOBJECTIVES:secondaryanalysesdataclinicaltrialwhereinfeedcowmilkdoubleincidenceextensivelyhydrolyzedproteindeterminewhetherinteractiveMETHODS:Anthropometrynumberdailyfeedsmonthly03LongitudinalfittedusinggeneralizedestimatingequationsseparatelogisticRESULTS:treatmentgroupsdifferstableacrossfirstFeedingsignificantinteractgroupHoweverdirectP = 0003CONCLUSIONS:differentialstylehighlightingself-regulatorycapabilitiesEarlyamongformula-fedinfants:Impact

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