Chemical composition, Aedes mosquito larvicidal activity, and repellent activity against Triatoma rubrofasciata of Severinia monophylla leaf essential oil.
Prabodh Satyal, Ho Viet Hieu, Nguyen Thi Hong Chuong, Nguyen Huy Hung, Le Hoang Sinh, Pham Van The, Thieu Anh Tai, Vu Thi Hien, William N Setzer
Author Information
Prabodh Satyal: Aromatic Plant Research Center, 230 N 1200 E, Suite 102, Lehi, UT, 84043, USA.
Ho Viet Hieu: Parasitology and Entomology Unit, Department of Medicine, Duy Tan University, 03 Quang Trung, Da Nang, Vietnam.
Nguyen Thi Hong Chuong: Center for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Da Nang, Vietnam.
Nguyen Huy Hung: Center for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Da Nang, Vietnam. huyhung2602@gmail.com.
Le Hoang Sinh: Center for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Da Nang, Vietnam.
Pham Van The: Center of Scientific Research and Practice, Thu Dau Mot University, No 06, Tran Van On street, Phu Hoa ward, Thu Dau Mot city, Binh Duong province, Vietnam.
Thieu Anh Tai: Department of Pharmacy, Duy Tan University, 03 - Quang Trung, Da Nang, Vietnam.
Vu Thi Hien: Faculty of Hydrometerology, Ho Chi Minh City University of Natural Resources and Environment, Ho Chi Minh City, Vietnam.
William N Setzer: Aromatic Plant Research Center, 230 N 1200 E, Suite 102, Lehi, UT, 84043, USA. wsetzer@chemistry.uah.edu. ORCID
Aedes aegypti and Ae. albopictus are key vectors in the spread of arboviruses such as dengue, chikungunya, yellow fever, and Zika. Triatoma rubrofasciata is an "assassin bug" whose populations and association with humans have dramatically increased and may represent a serious health concern. Control of insect vectors is a logical course of action to prevent the spread of these insect-borne infections. This work presents the leaf essential oil composition, mosquito larvicidal activities, and insect-repellent activity of Severinia monophylla. The essential oil of S. monophylla from Vietnam was obtained by hydrodistillation and analyzed by gas chromatography and mass spectrometry. The major components were sabinene, β-caryophyllene, bicyclogermacrene, germacrene D, (E)-nerolidol, globulol, and linalool. The leaf essential oil showed remarkable larvicidal activity against Ae. aegypti with LC (48 h) of 7.1 μg/mL and Ae. albopictus with LC (48 h) of 36 μg/mL. The essential oil also showed repellent activity on T. rubrofasciata at a concentration of 0.5%.
