Real-World Strategies to Treat Hypertension Associated with Pediatric Obesity.

Edem Binka, Tammy M Brady
Author Information
  1. Edem Binka: Pediatric Cardiology, Johns Hopkins University, Bloomberg Children's Center, 1800 Orleans Street, M2303, Baltimore, MD, 21287, USA. ebinka1@jhmi.edu.
  2. Tammy M Brady: Division of Pediatric Nephrology, Johns Hopkins University, David M. Rubenstein Child Health Building, 200 N. Wolfe Street, Baltimore, MD, 21287, USA.

Abstract

PURPOSE OF REVIEW: To review the most recent literature on current strategies for the treatment of hypertension associated with pediatric obesity.
RECENT FINDINGS: Over the last three decades, childhood and adolescent overweight and obesity prevalence in the USA has continued to rise. Unsurprisingly but rather disturbingly, this rising prevalence has been paralleled by an increase in cardiovascular disease (CVD) risk factors in childhood such as hypertension, dyslipidemia, and diabetes that become manifest earlier than previously reported. These childhood CVD risk factors are not only associated with target organ damage in childhood but also track into adulthood, increasing the risk of long-term CVD morbidity and mortality. There have been several mechanisms proposed to explain the role of obesity on the development of hypertension in childhood. However, central to the management of obesity-related hypertension is a multifaceted approach targeting lifestyle modifications and weight loss. Effective treatment often also requires a pharmacologic approach and rarely bariatric surgery.

Keywords

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Grants

  1. R56 HL139620/NHLBI NIH HHS
  2. T32 HD044355/NICHD NIH HHS
  3. T32 HL125239/NHLBI NIH HHS

MeSH Term

Adolescent
Adult
Child
Dyslipidemias
Humans
Hypertension
Life Style
Pediatric Obesity
Risk Factors
Weight Loss

Word Cloud

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