Sung Chul Park, Elin Julianti, Sungjin Ahn, Donghwa Kim, Sang Kook Lee, Minsoo Noh, Dong-Chan Oh, Ki-Bong Oh, And Jongheon Shin
Author Information
Sung Chul Park: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. sungchulpark@snu.ac.kr.
Elin Julianti: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. elin_julianti@fa.itb.ac.id.
Sungjin Ahn: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. sungjinahn@snu.ac.kr.
Donghwa Kim: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. dkim0719@snu.ac.kr.
Sang Kook Lee: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. sklee61@snu.ac.kr.
Minsoo Noh: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. minsoonoh@snu.ac.kr.
Dong-Chan Oh: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. dongchanoh@snu.ac.kr.
Ki-Bong Oh: Department of Agricultural Biotechnology, College of Agriculture and Life Science, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-921, Korea. ohkibong@snu.ac.kr.
And Jongheon Shin: Natural Products Research Institute, College of Pharmacy, Seoul National University, San 56-1, Sillim, Gwanak, Seoul 151-742, Korea. shinj@snu.ac.kr.
Six new phenalenone derivatives (⁻), along with five known compounds (⁻) of the herqueinone class, were isolated from a marine-derived fungus sp. The absolute configurations of these compounds were assigned based on chemical modifications and their specific rotations. 4-Hydroxysclerodin () and an acetone adduct of a triketone () exhibited moderate anti-angiogenetic and anti-inflammatory activities, respectively, while -peniciherqueinone () and isoherqueinone () exhibited moderate abilities to induce adipogenesis without cytotoxicity.
