An open electromagnetic tracking framework applied to targeted liver tumour ablation.

Stephen Hinds, Herman Alexander Jaeger, Richard Burke, Brodie O'Sullivan, Joseph Keane, Fabian Trauzettel, Bruno Marques, Stéphane Cotin, Brian Bird, Håkon Olav Leira, Erlend Fagertun Hofstad, Ole Vegard Solberg, Thomas Langø, Pádraig Cantillon-Murphy
Author Information
  1. Stephen Hinds: University College Cork, Cork, Ireland. ORCID
  2. Herman Alexander Jaeger: University College Cork, Cork, Ireland. h.jaeger@umail.ucc.ie. ORCID
  3. Richard Burke: University College Cork, Cork, Ireland.
  4. Brodie O'Sullivan: University College Cork, Cork, Ireland.
  5. Joseph Keane: Sunbeam Veterinary Hospital, Cork, Ireland.
  6. Fabian Trauzettel: University College Cork, Cork, Ireland.
  7. Bruno Marques: INRIA, Strasbourg, France.
  8. Stéphane Cotin: INRIA, Strasbourg, France.
  9. Brian Bird: Bon Secours Hospital, Cork, Ireland.
  10. Håkon Olav Leira: SINTEF, Trondheim, Norway.
  11. Erlend Fagertun Hofstad: SINTEF, Trondheim, Norway.
  12. Ole Vegard Solberg: SINTEF, Trondheim, Norway.
  13. Thomas Langø: SINTEF, Trondheim, Norway.
  14. Pádraig Cantillon-Murphy: University College Cork, Cork, Ireland.

Abstract

PURPOSE: Electromagnetic tracking is a core platform technology in the navigation and visualisation of image-guided procedures. The technology provides high tracking accuracy in non-line-of-sight environments, allowing instrument navigation in locations where optical tracking is not feasible. EMT can be beneficial in applications such as percutaneous radiofrequency ablation for the treatment of hepatic lesions where the needle tip may be obscured due to difficult liver environments (e.g subcutaneous fat or ablation artefacts). Advances in the field of EMT include novel methods of improving tracking system accuracy, precision and error compensation capabilities, though such system-level improvements cannot be readily incorporated in current therapy applications due to the 'blackbox' nature of commercial tracking solving algorithms.
METHODS: This paper defines a software framework to allow novel EMT designs, and improvements become part of the global design process for image-guided interventions. An exemplary framework is implemented in the Python programming language and demonstrated with the open-source Anser EMT system. The framework is applied in the preclinical setting though targeted liver ablation therapy on an animal model.
RESULTS: The developed framework was tested with the Anser EMT electromagnetic tracking platform. Liver tumour targeting was performed using the tracking framework with the CustusX navigation platform using commercially available electromagnetically tracked needles. Ablation of two tumours was performed with a commercially available ablation system. Necropsy of the tumours indicated ablations within 5 mm of the tumours.
CONCLUSIONS: An open-source framework for electromagnetic tracking was presented and effectively demonstrated in the preclinical setting. We believe that this framework provides a structure for future advancement in EMT system in and customised instrument design.

Keywords

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Grants

  1. 17/TIDA/4897/Science Foundation Ireland

MeSH Term

Algorithms
Animals
Biopsy, Needle
Catheter Ablation
Electromagnetic Phenomena
Equipment Design
Female
Liver
Liver Neoplasms
Needles
Reproducibility of Results
Software
Surgery, Computer-Assisted
Swine

Word Cloud

Created with Highcharts 10.0.0trackingframeworkEMTablationnavigationsystemplatformliverelectromagnetictumoursElectromagnetictechnologyimage-guidedprovidesaccuracyenvironmentsinstrumentapplicationsduenovelthoughimprovementstherapydesigndemonstratedopen-sourceAnserappliedpreclinicalsettingtargetedtumourperformedusingcommerciallyavailablePURPOSE:corevisualisationprocedureshighnon-line-of-sightallowinglocationsopticalfeasiblecanbeneficialpercutaneousradiofrequencytreatmenthepaticlesionsneedletipmayobscureddifficultegsubcutaneousfatartefactsAdvancesfieldincludemethodsimprovingprecisionerrorcompensationcapabilitiessystem-levelreadilyincorporatedcurrent'blackbox'naturecommercialsolvingalgorithmsMETHODS:paperdefinessoftwareallowdesignsbecomepartglobalprocessinterventionsexemplaryimplementedPythonprogramminglanguageanimalmodelRESULTS:developedtestedLivertargetingCustusXelectromagneticallytrackedneedlesAblationtwoNecropsyindicatedablationswithin5 mmCONCLUSIONS:presentedeffectivelybelievestructurefutureadvancementcustomisedopenImage-guidedinterventionSurgical

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