Recent advances in marburgvirus research.

Judith Olejnik, Elke Mühlberger, Adam J Hume
Author Information
  1. Judith Olejnik: Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA.
  2. Elke Mühlberger: Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA.
  3. Adam J Hume: Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA. ORCID

Abstract

Marburgviruses are closely related to ebolaviruses and cause a devastating disease in humans. In 2012, we published a comprehensive review of the first 45 years of research on marburgviruses and the disease they cause, ranging from molecular biology to ecology. Spurred in part by the deadly Ebola virus outbreak in West Africa in 2013-2016, research on all filoviruses has intensified. Not meant as an introduction to marburgviruses, this article instead provides a synopsis of recent progress in marburgvirus research with a particular focus on molecular biology, advances in animal modeling, and the use of Egyptian fruit bats in infection experiments.

Keywords

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Grants

  1. R01 AI133486/NIAID NIH HHS
  2. R21 AI135912/NIAID NIH HHS
  3. UC7 AI095321/NIAID NIH HHS

MeSH Term

Africa, Western
Animals
Biomedical Research
Chiroptera
Disease Models, Animal
Disease Outbreaks
Ebolavirus
Humans
Marburgvirus

Word Cloud

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