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The Journal of infectious diseases
07 02, 2019;220 (220 Suppl 1): S7-S11.

How to Address the Risk of HIV Transmission in Remission Studies With Treatment Interruption: The Low-Hanging Fruit Approach.

Nir Eyal
Author Information
  1. Nir Eyal: Center for Population-Level Bioethics, Rutgers University, New Brunswick, New Jersey.
PMID: 31264692 DOI: 10.1093/infdis/jiz163

Abstract

Some HIV remission studies include a treatment interruption that seriously risks infecting participants' sex partners with HIV. What, ethically, is owed to these nonparticipants? Until greater certainty emerges on what protections should be afforded nonparticipants of research studies, what I call a "low-hanging fruit" approach may help researchers and review bodies determine how to address infection risks to nonparticipants in these studies.

Keywords

HIV HIV cure-related studies analytic treatment interruption research ethics

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Grants

  1. R01 AI114617/NIAID NIH HHS

MeSH Term

Adult
Anti-HIV Agents
Coinfection
Female
HIV Infections
Humans
Male
Remission Induction
Risk Factors
Sexual Partners
Vaccines
Withholding Treatment

Chemicals

Anti-HIV Agents
Vaccines
Journal Article Research Support, N.I.H., Extramural
Article has an altmetric score of 1

Word Cloud

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