Efficacy of inactivation of human enteroviruses by dual-wavelength germicidal ultraviolet (UV-C) light emitting diodes (LEDs).
Hyoungmin Woo, Sara E Beck, Laura A Boczek, Kelsie Carlson, Nichole E Brinkman, Karl G Linden, Oliver R Lawal, Samuel L Hayes, Hodon Ryu
Author Information
Hyoungmin Woo: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
Sara E Beck: Department of Civil, Environmental, and Architectural Engineering, University of Colorado Boulder, UCB 428, Boulder, CO 80309, USA.
Laura A Boczek: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
Kelsie Carlson: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
Nichole E Brinkman: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
Karl G Linden: Department of Civil, Environmental, and Architectural Engineering, University of Colorado Boulder, UCB 428, Boulder, CO 80309, USA.
Oliver R Lawal: AquiSense Technologies, 4400 Olympic Boulevard, Erlanger, KY 41018, USA.
Samuel L Hayes: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
Hodon Ryu: United States Environmental Protection Agency, Office of Research and Development, 26 W. Martin Luther King Dr., Cincinnati, OH 45268, USA.
The efficacy of germicidal ultraviolet (UV-C) light emitting diodes (LEDs) was evaluated for inactivating human enteroviruses included on the United States Environmental Protection Agency (EPA)'s Contaminant Candidate List (CCL). A UV-C LED device, emitting at peaks of 260 nm and 280 nm and the combination of 260∣280 nm together, was used to measure and compare potential synergistic effects of dual wavelengths for disinfecting viral organisms. The 260 nm LED proved to be the most effective at inactivating the CCL enteroviruses tested. To obtain 2-log inactivation credit for the 260 nm LED, the fluences (UV doses) required are approximately 8 mJ/cm for coxsackievirus A10 and poliovirus 1, 10 mJ/cm for enterovirus 70, and 13 mJ/cm for echovirus 30. No synergistic effect was detected when evaluating the log inactivation of enteroviruses irradiated by the dual-wavelength UV-C LEDs.
