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Journal of immunology research
2019;2019 7453236.

IL-7 is a Key Driver Cytokine in Spondyloarthritis?

Rafaela Silva Guimarães Gonçalves, Angela Luzia Branco Pinto Duarte
Author Information
  1. Rafaela Silva Guimarães Gonçalves: Hospital das Clínicas de Pernambuco, Brazil. ORCID
  2. Angela Luzia Branco Pinto Duarte: Hospital das Clínicas de Pernambuco, Brazil. ORCID
PMID: 31276000 DOI: 10.1155/2019/7453236

Abstract

The rationale for a type 17 signature in the pathogenesis of spondyloarthritis (SpA) has been increasing and being ratified in studies recently. IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding of the disease as well as an important potential therapeutic target in patients with SpA.

References

  1. Bone Marrow Transplant. 1999 Apr;23(8):783-8 [PMID: 10231140]
  2. J Biol Chem. 1999 Jul 16;274(29):20709-16 [PMID: 10400705]
  3. Nat Immunol. 2000 Nov;1(5):426-32 [PMID: 11062503]
  4. Nat Med. 2001 Jan;7(1):73-9 [PMID: 11135619]
  5. Blood. 2001 May 15;97(10):2983-90 [PMID: 11342421]
  6. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8732-7 [PMID: 11447288]
  7. Blood. 2002 Jun 1;99(11):3892-904 [PMID: 12010786]
  8. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):125-30 [PMID: 12490655]
  9. Ann Rheum Dis. 2003 Feb;62(2):113-9 [PMID: 12525379]
  10. Nature. 2003 Feb 13;421(6924):744-8 [PMID: 12610626]
  11. Cell. 2003 Jun 13;113(6):685-700 [PMID: 12809600]
  12. J Exp Med. 2003 Dec 15;198(12):1951-7 [PMID: 14662908]
  13. J Biol Chem. 2004 Jul 2;279(27):28315-9 [PMID: 15133032]
  14. J Exp Med. 2005 Jan 17;201(2):233-40 [PMID: 15657292]
  15. J Immunol. 2005 Apr 15;174(8):4606-12 [PMID: 15814683]
  16. Arthritis Rheum. 2005 Jun;52(6):1700-10 [PMID: 15934068]
  17. Nat Immunol. 2005 Nov;6(11):1123-32 [PMID: 16200070]
  18. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14741-6 [PMID: 16203967]
  19. J Exp Med. 2006 Jun 12;203(6):1459-70 [PMID: 16717113]
  20. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13457-62 [PMID: 16938836]
  21. Arthritis Rheum. 2007 Mar;56(3):732-42 [PMID: 17328044]
  22. J Pathol. 2007 May;212(1):47-55 [PMID: 17370327]
  23. Arthritis Rheum. 2007 Aug;56(8):2492-502 [PMID: 17665400]
  24. Semin Immunol. 2007 Dec;19(6):353-61 [PMID: 18023589]
  25. Clin Exp Immunol. 1991 Apr;84(1):78-82 [PMID: 1826649]
  26. Clin Immunol Immunopathol. 1991 Apr;59(1):165-72 [PMID: 1826866]
  27. Arthritis Rheum. 2008 Nov;58(11):3430-5 [PMID: 18975340]
  28. J Exp Med. 2009 Jan 16;206(1):35-41 [PMID: 19114665]
  29. Nat Immunol. 2009 Mar;10(3):314-24 [PMID: 19182808]
  30. Immunity. 2009 Mar 20;30(3):447-57 [PMID: 19285437]
  31. Immunity. 2009 Aug 21;31(2):331-41 [PMID: 19682929]
  32. Nat Med. 2010 Feb;16(2):191-7 [PMID: 20062065]
  33. J Exp Med. 2010 Feb 15;207(2):273-80 [PMID: 20142427]
  34. Nature. 2010 Apr 29;464(7293):1371-5 [PMID: 20393462]
  35. Blood. 2011 Jul 21;118(3):586-93 [PMID: 21606479]
  36. Lancet. 2011 Jun 18;377(9783):2127-37 [PMID: 21684383]
  37. Arthritis Res Ther. 2011 Jun 20;13(3):R95 [PMID: 21689402]
  38. Nat Immunol. 2011 Jun;12(6):478-84 [PMID: 21739670]
  39. Arthritis Rheum. 2012 May;64(5):1420-9 [PMID: 22144400]
  40. Nat Med. 2012 Jul 01;18(7):1069-76 [PMID: 22772566]
  41. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17549-54 [PMID: 23047700]
  42. Annu Rev Pathol. 2013 Jan 24;8:477-512 [PMID: 23157335]
  43. J Immunol. 2013 Apr 1;190(7):3142-52 [PMID: 23447689]
  44. J Exp Med. 2014 Jan 13;211(1):89-104 [PMID: 24395888]
  45. Ann Rheum Dis. 2014 Jun;73(6):990-9 [PMID: 24482301]
  46. Autoimmun Rev. 2014 Dec;13(12):1174-81 [PMID: 25151974]
  47. Int Immunol. 1989;1(5):526-31 [PMID: 2518727]
  48. J Exp Med. 1989 Mar 1;169(3):707-16 [PMID: 2522498]
  49. Int J Rheum Dis. 2016 Apr;19(4):392-404 [PMID: 25545680]
  50. Nature. 2015 Jan 15;517(7534):293-301 [PMID: 25592534]
  51. Annu Rev Immunol. 2015;33:607-42 [PMID: 25665079]
  52. Curr Rheumatol Rep. 2015 May;17(5):30 [PMID: 25874346]
  53. Ann Rheum Dis. 2015 Sep;74(9):1739-47 [PMID: 25902790]
  54. Adv Immunol. 2015;127:145-201 [PMID: 26073984]
  55. Clin Immunol. 2015 Dec;161(2):163-9 [PMID: 26244610]
  56. N Engl J Med. 2015 Oct;373(14):1329-39 [PMID: 26422723]
  57. Autoimmunity. 2016 Nov;49(7):435-450 [PMID: 27050731]
  58. Clin Exp Immunol. 2016 Aug;185(2):125-32 [PMID: 27159882]
  59. Ann Rheum Dis. 2016 Dec;75(12):2124-2132 [PMID: 27165176]
  60. Nat Rev Dis Primers. 2015 Jul 09;1:15013 [PMID: 27188328]
  61. PLoS One. 2016 Jul 14;11(7):e0158905 [PMID: 27415816]
  62. Ann Rheum Dis. 2016 Dec;75(12):2057-2059 [PMID: 27474762]
  63. Proc Natl Acad Sci U S A. 1989 Mar;86(5):1634-8 [PMID: 2784210]
  64. Eur J Immunol. 1989 Apr;19(4):783-6 [PMID: 2786474]
  65. Hum Genet. 1989 Jul;82(4):371-2 [PMID: 2786840]
  66. Arthritis Rheumatol. 2017 Jul;69(7):1480-1494 [PMID: 28296284]
  67. Clin Immunol. 2017 Oct;183:207-212 [PMID: 28390966]
  68. Front Immunol. 2017 Jun 30;8:761 [PMID: 28713381]
  69. Ann Rheum Dis. 2018 Feb;77(2):175-187 [PMID: 28765121]
  70. Nat Commun. 2017 Aug 10;8(1):231 [PMID: 28794449]
  71. J Autoimmun. 2018 Feb;87:26-37 [PMID: 29203226]
  72. Autoimmunity. 2018 Feb;51(1):1-9 [PMID: 29256263]
  73. Mediators Inflamm. 2018 Feb 12;2018:2403935 [PMID: 29670461]
  74. J Rheumatol Suppl. 2018 Jun;94:36-39 [PMID: 29858352]
  75. Lancet. 2018 Jun 2;391(10136):2273-2284 [PMID: 29893226]
  76. J Clin Invest. 2019 Apr 2;130:1910-1925 [PMID: 30939120]
  77. Nature. 1994 Aug 4;370(6488):341-7 [PMID: 8047140]
  78. Blood. 1993 Dec 15;82(12):3686-94 [PMID: 8260705]
  79. Annu Rev Biochem. 1998;67:753-91 [PMID: 9759503]
  80. Nat Genet. 1998 Dec;20(4):394-7 [PMID: 9843216]

MeSH Term

Adaptive Immunity
Animals
Cytokines
Disease Susceptibility
Fibrosis
Humans
Immunity, Innate
Interleukin-7
Protein Binding
Receptors, Cytokine
Signal Transduction
Spondylarthritis
T-Lymphocyte Subsets

Chemicals

Cytokines
Interleukin-7
Receptors, Cytokine
Journal Article Review
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0SpAIL-7targetrationaletype17signaturepathogenesisspondyloarthritisincreasingratifiedstudiesrecentlycytokinewhoseabilitystimulateIL-17productioninnateadaptiveimmunitycellsmadepromisingbetterunderstandingdiseasewellimportantpotentialtherapeuticpatientsKeyDriverCytokineSpondyloarthritis?

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