Relationship between dental plaque formation and salivary cortisol level in pregnant women.
Azita Tiznobaik, Safoura Taheri, Parviz Torkzaban, Ali Ghaleiha, Ali Reza Soltanian, Reza Omrani, Mehdi Shirinzad
Author Information
Azita Tiznobaik: Department of Reproductive Health, Faculty of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran.Iran.
Safoura Taheri: Department of Midwifery, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam.Iran.
Parviz Torkzaban: Department of Periodontics, Faculty of Dentistry, Hamadan University of Medical Sciences, Hamadan.Iran.
Ali Ghaleiha: Research center for Behavioral disorders and substance abuse, Hamadan University of Medical Sciences, Hamadan.Iran.
Ali Reza Soltanian: Modeling of non-communicable diseases research center, school of public health, Hamadan University of Medical science, Hamadan.Iran.
Reza Omrani: Department of Restorative Dentistry, Faculty of Dentistry, Hamadan University of Medical Sciences, Hamadan.Iran.
Mehdi Shirinzad: Department of Restorative Dentistry, Faculty of Dentistry, Hamadan University of Medical Sciences, Hamadan.Iran.
PURPOSE: Understanding how increased level of salivary cortisol contributes to the development of dental biofilm during pregnancy can help inthe prevention of dental caries and periodontal diseases. This study aims to evaluate the relationship between salivary cortisol level and dental biofilm formation in pregnant women. PATIENTS AND METHODS: This descriptive-analytic study was conducted in Hamadan, Iran in 2011. Forty consecutive pregnant women with no history of abortion, stillbirth, or any known physical or psychological disorders at weeks 25 and 33 of gestation were included. Salivary samples were collected for measurement of cortisol levels by Enzyme Linked Immunoabsorbent Assay (ELISA) method. The amount and extension of dental biofilms were determined by using a disclosing agent. Data were analyzed using descriptive and analytical statistics in SPSS version 16. RESULTS: The mean levels of salivary cortisol at weeks 25 and 33 of gestation were respectively, 2.45 ± 1.56 μg/dl and 5.24 ± 4.07 μg/dl which demonstrates a significant difference (P<0.001). Evaluation of dental biofilm at two time intervals revealed a significant increase in amount of dental biofilm at week 33 of gestational period (34.65 ± 10.9% vs. 42.45 ± 12.35%, P<0.001). Elevated levels of dental biofilm were significantly correlated with salivary cortisol levels at week 33 (r=0.494, P=0.001),however, it was not significant at week 25 of gestation (r=0.148, P=0.361). CONCLUSION: The findings suggested that increased levels of salivary cortisol can predict dental biofilm formation and accumulation in pregnant women in the last weeks of gestation.
