Changes in Cognitive Function and Risk Factors for Cognitive Impairment of the Elderly in China: 2005-2014.

Qilin Zhang, Yanli Wu, Tiankuo Han, Erpeng Liu
Author Information
  1. Qilin Zhang: Centre for Social Security Studies, Wuhan University, Wuhan 430072, China. ORCID
  2. Yanli Wu: Centre for Social Security Studies, Wuhan University, Wuhan 430072, China.
  3. Tiankuo Han: Centre for Social Security Studies, Wuhan University, Wuhan 430072, China.
  4. Erpeng Liu: Centre for Social Security Studies, Wuhan University, Wuhan 430072, China. whubest@whu.edu.cn. ORCID

Abstract

The cognitive function of the elderly has become a focus of public health research. Little is known about the changes of cognitive function and the risk factors for cognitive impairment in the Chinese elderly; thus, the purposes of this study are as follows: (1) to describe changes in cognitive function in the Chinese elderly from 2005-2014 and (2) to explore risk factors for cognitive impairment of the Chinese elderly. A total of 2603 participants aged 64 years and above participated in the Chinese Longitudinal Healthy Longevity Survey (CLHLS) and were followed up from 2005 to 2014. Cognitive function and cognitive impairment were assessed using the Chinese version of the Mini-Mental State Examination (MMSE). Binary logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence intervals (CI) of cognitive impairment. Results revealed that the cognitive function of the Chinese elderly shows diversified changes: deterioration (55.09%), unchanged (17.21%) and improvement (27.70%). In addition, there are significant demographic differences in gender, age, education, marriage and other aspects when it comes to the changes of cognitive function in Chinese elderly. In the binary logistic regression analysis, female, increased age, lower education level, no spouse, less income, worse PWB (psychological well-being), less fresh fruit and vegetable intake, more activities of daily living (ADL) limitations, lower social engagement were significantly associated with higher odds for cognitive impairment. Various interventions should be implemented to maintain cognitive function in Chinese elderly.

Keywords

References

  1. Am J Epidemiol. 2009 Aug 1;170(3):331-42 [PMID: 19605514]
  2. Health Soc Care Community. 2017 May;25(3):1160-1168 [PMID: 28178751]
  3. Front Aging Neurosci. 2014 May 23;6:94 [PMID: 24904408]
  4. Psychol Bull. 2015 Mar;141(2):364-403 [PMID: 25602273]
  5. SSM Popul Health. 2016 Dec;2:793-797 [PMID: 27917398]
  6. J Nutr Health Aging. 2007 Mar-Apr;11(2):132-52 [PMID: 17435956]
  7. BMJ. 2019 Apr 17;365:l1495 [PMID: 30995986]
  8. Br Med Bull. 2009;92:135-52 [PMID: 19776035]
  9. Lancet. 2017 Apr 22;389(10079):1619-1629 [PMID: 28285816]
  10. Arch Neurol. 2007 Dec;64(12):1734-40 [PMID: 18071036]
  11. Int J Environ Res Public Health. 2019 May 14;16(10): [PMID: 31091753]
  12. BMJ. 2009 Jul 02;339:b2462 [PMID: 19574312]
  13. Neuropsychology. 2005 Jul;19(4):520-31 [PMID: 16060827]
  14. BMJ. 2004 Sep 4;329(7465):539 [PMID: 15304383]
  15. Int J Geriatr Psychiatry. 2013 Jun;28(6):597-606 [PMID: 22968965]
  16. Mayo Clin Proc. 2012 May;87(5):437-42 [PMID: 22560523]
  17. J Psychiatr Res. 1975 Nov;12(3):189-98 [PMID: 1202204]
  18. Arch Phys Med Rehabil. 2004 Oct;85(10):1694-704 [PMID: 15468033]
  19. Arch Gerontol Geriatr. 2015 Jan-Feb;60(1):196-200 [PMID: 25456889]
  20. Curr Psychiatry Rep. 2017 Aug 10;19(9):64 [PMID: 28795386]
  21. Int J Environ Res Public Health. 2018 Jan 30;15(2): [PMID: 29385773]
  22. Int J Environ Res Public Health. 2015 Jul 17;12(7):8281-94 [PMID: 26193295]
  23. Eur Arch Psychiatry Clin Neurosci. 1999;249 Suppl 3:43-5 [PMID: 10654099]
  24. Physiol Behav. 2019 Apr 1;202:8-13 [PMID: 30684588]
  25. Alzheimers Res Ther. 2016 Jul 30;8(1):23 [PMID: 27473681]
  26. Int Psychogeriatr. 2014 Jul;26(7):1059-64 [PMID: 24846782]
  27. J Health Soc Behav. 2011 Dec;52(4):430-43 [PMID: 22144732]
  28. Brain. 2005 May;128(Pt 5):1093-101 [PMID: 15774508]
  29. Arch Gerontol Geriatr. 2017 May - Jun;70:219-229 [PMID: 28219846]
  30. J Nutr Health Aging. 2019;23(1):14-20 [PMID: 30569063]
  31. Beijing Da Xue Xue Bao Yi Xue Ban. 2015 Jun 18;47(3):443-9 [PMID: 26080873]
  32. Psychol Aging. 2007 Sep;22(3):525-545 [PMID: 17874952]
  33. J Gerontol A Biol Sci Med Sci. 2014 Nov;69 Suppl 2:S82-9 [PMID: 25378453]
  34. Aging (Albany NY). 2016 Jun;8(6):1250-8 [PMID: 27294343]
  35. Lancet Glob Health. 2019 May;7(5):e596-e603 [PMID: 31000129]
  36. Age Ageing. 2011 Nov;40(6):684-9 [PMID: 21890481]
  37. Ir J Psychol Med. 2019 Jun;36(2):85-88 [PMID: 31187723]
  38. J Alzheimers Dis. 2009;17(4):921-7 [PMID: 19542607]
  39. Dement Geriatr Cogn Disord. 2008;26(2):153-60 [PMID: 18679030]
  40. Int J Geriatr Psychiatry. 2011 Jun;26(6):558-63 [PMID: 20878675]
  41. J Aging Health. 2008 Jun;20(4):456-77 [PMID: 18448687]
  42. Arch Gerontol Geriatr. 2010 Sep-Oct;51(2):143-8 [PMID: 19833398]
  43. J Gerontol B Psychol Sci Soc Sci. 2016 May;71(3):538-50 [PMID: 25617400]
  44. Dement Geriatr Cogn Disord. 2018;45(3-4):190-197 [PMID: 29870984]
  45. N Engl J Med. 2016 Feb 11;374(6):523-32 [PMID: 26863354]
  46. Am J Med Genet C Semin Med Genet. 2016 Mar;172C(1):34-40 [PMID: 26818018]
  47. PLoS One. 2013 Jun 11;8(6):e66252 [PMID: 23776645]
  48. Zhonghua Yu Fang Yi Xue Za Zhi. 2013 Sep;47(9):811-5 [PMID: 24351561]
  49. JAMA Intern Med. 2017 Aug 1;177(8):1146-1153 [PMID: 28586818]
  50. J Am Med Dir Assoc. 2016 Feb;17(2):184.e9-14 [PMID: 26778491]
  51. Eur J Epidemiol. 2013 May;28(5):405-16 [PMID: 23532744]
  52. Sci Rep. 2018 Jul 5;8(1):10226 [PMID: 29977058]
  53. Arch Gerontol Geriatr. 2019 Mar - Apr;81:222-233 [PMID: 30654180]
  54. Eur J Clin Nutr. 2018 Oct;72(10):1336-1344 [PMID: 29235561]
  55. J Gerontol A Biol Sci Med Sci. 2017 Jul 1;72(suppl_1):S5-S10 [PMID: 28575265]
  56. Nat Commun. 2016 Apr 19;7:11398 [PMID: 27092707]

MeSH Term

Activities of Daily Living
Aged
Aged, 80 and over
China
Cognition
Cognitive Dysfunction
Female
Humans
Longevity
Longitudinal Studies
Male
Odds Ratio
Risk Factors

Word Cloud

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