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Journal of cancer survivorship : research and practice
Oct, 2019;13 (5): 739-748.

Prevalence of cardiovascular disease and risk factors, quality of life, and health behaviors of cancer survivors and their spouses: findings from MEPS.

Lixin Song, Ting Guan, Peiran Guo, Thomas C Keyserling, Courtney Van Houtven, Xianming Tan
Author Information
  1. Lixin Song: School of Nursing, University of North Carolina at Chapel Hill, Carrington Hall, S Columbia St, Chapel Hill, NC, 27599-7460, USA. lsong@unc.edu. ORCID
  2. Ting Guan: School of Social Work, University of North Carolina at Chapel Hill, Tate-Turner-Kuralt Building, 325 Pittsboro Street #3550, Chapel Hill, NC, 27599, USA.
  3. Peiran Guo: Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 135 Dauer Dr, Chapel Hill, NC, 27599, USA.
  4. Thomas C Keyserling: School of Medicine, University of North Carolina at Chapel Hill, 321 S Columbia Street, Chapel Hill, NC, 27599, USA.
  5. Courtney Van Houtven: Durham Center for Health Services Research in Primary Care, VA Medical Center, 508 Fulton Street, Durham, NC, 27705, USA.
  6. Xianming Tan: Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 450 West Drive N.C, Chapel Hill, NC, 27599, USA.
PMID: 31440947 DOI: 10.1007/s11764-019-00792-8

Abstract

PURPOSE: Few population-based studies have examined the prevalence of cardiovascular disease (CVD) and risk factors, quality of life (QOL), and health behaviors of cancer survivors and their spouses. This case-control study aimed to fill this gap using the data from a set of large-scale surveys of individuals and families across the USA.
METHODS: Data were obtained from the 2010-2015 Medical Expenditure Panel Survey (MEPS). Using one-to-many (1:5) propensity score matching, we identified cancer survivors (N = 1037) and noncancer-matched controls (N = 5185), as well as survivor spouses (N = 1038) and matched controls (N = 5190). We used weighted multivariable logistic and linear regressions to examine the categorical and numerical outcomes.
RESULTS: Compared with noncancer controls, survivors have higher rates of stroke (p < .05), hypertension (p < .05), high cholesterol (p < .01), fair or poor health (p < .0001), and report self-reported worse physical QOL scores (PCS) (p < .0001). A higher percentage of survivors report receiving BP checks (p < .01), serum cholesterol assessments (p < .001), routine physical checkups (p < .01), blood stool tests (p < .05), colonoscopies (p < .0001), and flu vaccinations (p < .05). Survivor spouses, compared to their respective matched controls, reported higher rates of serum cholesterol testing (p < .001), routine physical checkups (p < .01), and flu vaccinations (p < .01).
CONCLUSIONS: Compared to the general population, cancer survivors are at higher risk for CVD, report worse physical QOL, and, along with their spouses, more frequently receive certain preventive health care services.
IMPLICATIONS FOR CANCER SURVIVORS: There is a need for intervention to more fully engage cancer survivors and spouses in lifestyle behavior change associated with decreased CVD and related risk factors and improved QOL.

Keywords

Cancer Cardiovascular disease Family Health behavior propensity score matching Quality of life

References

  1. Psychol Health Med. 2018 Jun;23(5):548-554 [PMID: 28984149]
  2. Arch Environ Health. 1966 Feb;12(2):246-66 [PMID: 5322534]
  3. J Clin Oncol. 2016 Apr 1;34(10):1122-30 [PMID: 26834065]
  4. CA Cancer J Clin. 2016 Jul;66(4):271-89 [PMID: 27253694]
  5. Cancer. 2013 Jun 1;119 Suppl 11:2160-9 [PMID: 23695928]
  6. Am J Prev Med. 2010 Jan;38(1):61-9 [PMID: 20117558]
  7. Ann Oncol. 2017 Feb 1;28(2):400-407 [PMID: 27831506]
  8. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD007566 [PMID: 22895961]
  9. Lancet. 1994 Jun 11;343(8911):1454-9 [PMID: 7911176]
  10. Support Care Cancer. 2011 Jul;19(7):919-27 [PMID: 20445996]
  11. Healthcare (Basel). 2017 Apr 26;5(2): [PMID: 28445438]
  12. Brain Behav Immun. 2012 Feb;26(2):228-33 [PMID: 21807090]
  13. Cancer. 2014 May 1;120(9):1290-314 [PMID: 24343171]
  14. J Acad Nutr Diet. 2018 Jan;118(1):74-100.e11 [PMID: 29111090]
  15. Neuropsychiatr Dis Treat. 2018 Jun 28;14:1697-1704 [PMID: 29988736]
  16. J Gen Intern Med. 2015 Oct;30(10):1511-6 [PMID: 25832617]
  17. Oncol Nurs Forum. 2015 Jan;42(1):54-62 [PMID: 25542321]
  18. CA Cancer J Clin. 2015 May-Jun;65(3):167-89 [PMID: 25683894]
  19. Int J Environ Res Public Health. 2012 Feb;9(2):391-407 [PMID: 22470299]
  20. EJC Suppl. 2014 Jun;12(1):18-28 [PMID: 26217163]
  21. Qual Life Res. 2008 Aug;17(6):845-55 [PMID: 18506598]
  22. Eur Urol. 2014 May;65(5):887-94 [PMID: 23962747]
  23. J Cancer Surviv. 2017 Apr;11(2):264-273 [PMID: 27854007]
  24. Health Serv Res. 2008 Feb;43(1 Pt 1):96-116 [PMID: 18211520]
  25. Cancer. 2006 Jan 1;106(1):17-27 [PMID: 16311986]
  26. J Cancer Surviv. 2010 Mar;4(1):20-32 [PMID: 19902360]
  27. J Clin Oncol. 2005 Dec 1;23(34):8884-93 [PMID: 16314649]
  28. Circulation. 2012 Apr 10;125(14):1742-7 [PMID: 22415143]
  29. MMWR Surveill Summ. 2012 Jan 20;61(1):1-23 [PMID: 22258477]
  30. Am J Epidemiol. 2009 Jan 1;169(1):1-8 [PMID: 18845552]
  31. N Engl J Med. 2018 Oct 04;379(14):1387 [PMID: 30285331]
  32. Epidemiology. 2011 Mar;22(2):282 [PMID: 21293212]
  33. Acta Oncol. 2015 May;54(5):727-34 [PMID: 25761088]
  34. Health Educ Behav. 2018 Feb;45(1):90-100 [PMID: 28443370]
  35. Psychooncology. 2015 Oct;24(10):1250-1257 [PMID: 26060053]
  36. Pharmacoepidemiol Drug Saf. 2012 May;21 Suppl 2:69-80 [PMID: 22552982]
  37. Prev Chronic Dis. 2010 Jan;7(1):A09 [PMID: 20040224]
  38. Cancer. 2008 Jun;112(11):2475-82 [PMID: 18428195]
  39. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD008465 [PMID: 22895974]
  40. Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1089-97 [PMID: 21467238]
  41. Cancer. 2016 Jul 1;122(13):1987-95 [PMID: 26991807]
  42. J Clin Oncol. 2016 Aug 10;34(23):2743-9 [PMID: 27217451]
  43. Psychooncology. 2012 Mar;21(3):273-81 [PMID: 22383269]
  44. J Cancer Surviv. 2012 Dec;6(4):407-19 [PMID: 23011572]
  45. Circulation. 2006 Feb 14;113(6):898-918 [PMID: 16380542]
  46. Breast Cancer Res Treat. 2014 Jan;143(2):219-26 [PMID: 24337598]
  47. J Natl Compr Canc Netw. 2016 Jun;14(6):715-24 [PMID: 27283164]

Grants

  1. R01 NR016990/NINR NIH HHS
  2. R21 CA212516/NCI NIH HHS

MeSH Term

Adolescent
Adult
Aged
Aged, 80 and over
Cancer Survivors
Cardiovascular Diseases
Case-Control Studies
Female
Health Behavior
Humans
Life Style
Male
Middle Aged
Prevalence
Preventive Health Services
Quality of Life
Risk Factors
Spouses
Surveys and Questionnaires
Survivors
United States
Young Adult
Journal Article
Article has an altmetric score of 2

Word Cloud

Created with Highcharts 10.0.0p <survivorscancerspouses01riskQOLhealthcontrolshigher05physicaldiseaseCVDfactorslifecholesterol0001reportcardiovascularqualitybehaviorsMEPSscorematchingmatchedComparedratesworseserum001routinecheckupsfluvaccinationsPURPOSE:population-basedstudiesexaminedprevalencecase-controlstudyaimedfillgapusingdatasetlarge-scalesurveysindividualsfamiliesacrossUSAMETHODS:Dataobtained2010-2015MedicalExpenditurePanelSurveyUsingone-to-many1:5propensityidentifiedN = 1037noncancer-matchedN = 5185wellsurvivorN = 1038N = 5190usedweightedmultivariablelogisticlinearregressionsexaminecategoricalnumericaloutcomesRESULTS:noncancerstrokehypertensionhighfairpoorself-reportedscoresPCSpercentagereceivingBPchecksassessmentsbloodstooltestscolonoscopiesSurvivorcomparedrespectivereportedtestingCONCLUSIONS:generalpopulationalongfrequentlyreceivecertainpreventivecareservicesIMPLICATIONSFORCANCERSURVIVORS:needinterventionfullyengagelifestylebehaviorchangeassociateddecreasedrelatedimprovedPrevalencespouses:findingsCancerCardiovascularFamilyHealthbehavior propensityQuality

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