Associations of decision making abilities with blood pressure values in older adults.

Melissa Lamar, Robert S Wilson, Lei Yu, Christopher C Stewart, David A Bennett, Patricia A Boyle
Author Information
  1. Melissa Lamar: Rush Alzheimer's Disease Center Department of Psychiatry and Behavioral Sciences Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Abstract

OBJECTIVES: Decision making, key to successful aging, has implications for financial success, physical health, and well being. While poor decision making has been linked with increased risk of mortality, age-related cognitive decline, and dementia, less is known regarding its associations with chronic disease indicators. We investigated the associations of decision making with blood pressure (BP) values [i.e., SBP, mean arterial pressure (MAP), and pulse pressure (PP), separately] in a community-based cohort study of aging.
METHODS: Participants were 908 nondemented older adults (age ∼81 years; 75% women) from the Rush Memory and Aging Project. Decision making was measured using questions designed to simulate materials used in financial and healthcare settings in the real world and yielded a total score and domain-specific health and financial decision making scores. Two seated and one standing BP measurement were taken with all three contributing to average SBP, MAP that is, [SBP + (2 × DBP)]/3, and PP, that is, SBP - DBP. Participants were queried about hypertension status and antihypertension medications were visually inspected and coded. Participants also underwent medical history and cognitive assessments.
RESULTS: In separate multivariable linear regression models, total decision making scores were inversely associated with SBP, MAP, and PP after adjusting for age, sex, education, antihypertension medication use, diabetes, and cumulative cardiovascular disease burden (P values = 0.03). Decision making remained associated with these BP values after additional adjustment for global cognition.
CONCLUSION: Poorer decision making is associated with higher BP values in nondemented older adults.

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Grants

  1. R01 AG017917/NIA NIH HHS
  2. R01 AG033678/NIA NIH HHS
  3. R01 AG034374/NIA NIH HHS

MeSH Term

Aged, 80 and over
Aging
Antihypertensive Agents
Blood Pressure
Cognitive Dysfunction
Cohort Studies
Decision Making
Female
Humans
Hypertension
Male

Chemicals

Antihypertensive Agents

Word Cloud

Created with Highcharts 10.0.0makingdecisionpressureBPvaluesDecisionfinancialSBPMAPPPParticipantsolderadultsassociatedaginghealthcognitiveassociationsdiseasebloodnondementedagetotalscoresantihypertensionOBJECTIVES:keysuccessfulimplicationssuccessphysicalwellpoorlinkedincreasedriskmortalityage-relateddeclinedementialessknownregardingchronicindicatorsinvestigated[iemeanarterialpulseseparately]community-basedcohortstudyMETHODS:908∼81years75%womenRushMemoryAgingProjectmeasuredusingquestionsdesignedsimulatematerialsusedhealthcaresettingsrealworldyieldedscoredomain-specificTwoseatedonestandingmeasurementtakenthreecontributingaverage[SBP + 2 × DBP]/3SBP - DBPqueriedhypertensionstatusmedicationsvisuallyinspectedcodedalsounderwentmedicalhistoryassessmentsRESULTS:separatemultivariablelinearregressionmodelsinverselyadjustingsexeducationmedicationusediabetescumulativecardiovascularburdenPvalues = 003remainedadditionaladjustmentglobalcognitionCONCLUSION:PoorerhigherAssociationsabilities

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