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Revista latino-americana de enfermagem
2019;27 e3217.

Patient safety in primary health care and polypharmacy: cross-sectional survey among patients with chronic diseases.

Lorena Ulhôa Araújo, Delba Fonseca Santos, Emerson Cotta Bodevan, Hellen Lilliane da Cruz, Jacqueline de Souza, Neila Márcia Silva-Barcellos
Author Information
  1. Lorena Ulhôa Araújo: Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Farmácia, Diamantina, Minas Gerais, Brazil. ORCID
  2. Delba Fonseca Santos: Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Farmácia, Diamantina, Minas Gerais, Brazil. ORCID
  3. Emerson Cotta Bodevan: Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Matemática e Estatística, Diamantina, Minas Gerais, Brazil. ORCID
  4. Hellen Lilliane da Cruz: Universidade Federal dos Vales do Jequitinhonha e Mucuri, Departamento de Farmácia, Diamantina, Minas Gerais, Brazil. ORCID
  5. Jacqueline de Souza: Universidade Federal de Ouro Preto, Escola de Farmácia, Ouro Preto, Minas Gerais, Brazil. ORCID
  6. Neila Márcia Silva-Barcellos: Universidade Federal de Ouro Preto, Escola de Farmácia, Ouro Preto, Minas Gerais, Brazil. ORCID
PMID: 31826159 DOI: 10.1590/1518-8345.3123.3217

Abstract

OBJECTIVE: to characterize and determine the polypharmacy prevalence in patients with chronic diseases and to identify the factors associated, in order to improvement of pharmaceutical care focused on patient safety.
METHODS: cross-sectional study included 558 patients, covered by primary health care, using a household and structured questionnaire. We analyzed the data on polypharmacy and its clinical and socioeconomic factors. Poisson regression analysis with robust variance was applied, with results expressed in prevalence ratio.
RESULTS: the results showed that polypharmacy (consumption of four or more drugs) was of 37.6%. The prevalence ratio analyses identified independent variables associated with polypharmacy: age (3.05), economic strata (0.33), way of medication acquisition through a combination of out-of-pocket and Brazilian public health system (1.44), diabetes and hypertension (2.11), comorbidities (coronary artery disease 2.26) and hospital admission (1.73). In the analyses, inappropriate medication use of the 278 patients (≥ 65 years) was associated with polypharmacy (prevalence ratio 4.04).
CONCLUSION: polypharmacy study becomes an opportunity to guide the strategies for the patient safety to promote the medication without harm in chronic diseases.

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MeSH Term

Adolescent
Adult
Aged
Brazil
Chronic Disease
Comorbidity
Cross-Sectional Studies
Diabetes Mellitus
Female
Humans
Hypertension
Male
Middle Aged
Polypharmacy
Potentially Inappropriate Medication List
Prevalence
Primary Health Care
Socioeconomic Factors
Surveys and Questionnaires
Young Adult
Journal Article

Word Cloud

Created with Highcharts 10.0.0polypharmacyprevalencepatientschronicdiseasesassociatedcaresafetyhealthratiomedicationfactorspatientcross-sectionalstudyprimaryresultsanalysespolypharmacy:12OBJECTIVE:characterizedetermineidentifyorderimprovementpharmaceuticalfocusedMETHODS:included558coveredusinghouseholdstructuredquestionnaireanalyzeddataclinicalsocioeconomicPoissonregressionanalysisrobustvarianceappliedexpressedRESULTS:showedconsumptionfourdrugs376%identifiedindependentvariablesage305economicstrata033wayacquisitioncombinationout-of-pocketBrazilianpublicsystem44diabeteshypertension11comorbiditiescoronaryarterydisease26hospitaladmission73inappropriateuse278≥65years404CONCLUSION:becomesopportunityguidestrategiespromotewithoutharmPatientsurveyamong

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