Facile synthesis of a cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application in the electrochemical detection of ofloxacin.
Feng Luan: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn.
Yunfei Wang: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn.
Shuang Zhang: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn.
Xuming Zhuang: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn. ORCID
Chunyuan Tian: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn.
Xiuli Fu: College of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China. xmzhuang@iccas.ac.cn.
Lingxin Chen: Shandong Key Laboratory of Coastal Environmental Processes, CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China. lxchen@yic.ac.cn and Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China and Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China. ORCID
A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and platinum nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, elemental mapping, and Raman spectroscopy. The sensor was then evaluated for its ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOF had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration range of 0.08-100 μM and a low detection limit of 0.037 μM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.
